2022年5月2日，中国台湾地区扩展mRNA新冠疫苗紧急使用授权至5-11岁儿童。此外，澳门特别行政区政府也计划将于5月24日起提供儿童mRNA疫苗复必泰接种。 在中国内地，由复星医药和百欧恩泰联合开展的BNT162b2的临床进展也备受关注，近期，在临床试验数据库ClinicalTrials.gov上的信息显示，BNT162b2在中国境内的II期临床试验...
截至6个月随访期时,虽然疫苗效力逐渐减弱,但BNT162b2安全性仍然良好,并且仍然可以非常有效地预防COVID-19。(由BioNTech和辉瑞资助;在ClinicalTrials.gov注册号为NCT04368728。) Conclusions Through 6 months of follow-up and despite a grad...
中位2个月期间的安全性与其他病毒疫苗相似。(由BioNTech和辉瑞资助;在ClinicalTrials.gov注册号为NCT04368728。) Conclusions A two-dose regimen of BNT162b2 conferred 95% protection against Covid-19 in persons 16 years of age or older....
“复必泰”,是mRNA新冠疫苗BNT162b2在中国的商品中文名称。 美国临床试验数据库(ClinicalTrials.gov)显示,5月10日,复必泰在中国的临床试验更新了研究进展,II期临床试验的状态从“进行中”变更为“已完成”,数据显示,这项临床研究在2022年1月9日完成。 2020年3 月 15 日疫情初期,复星医药向BioNTech投资 1.35 亿美...
在中国内地,由复星医药和百欧恩泰联合开展的BNT162b2的临床进展也备受关注,近期,在临床试验数据库ClinicalTrials.gov上的信息显示,BNT162b2在中国境内的II期临床试验状态显示“已完成”,该临床试验共招募了950多名健康受试者,目的在于评估该疫苗的安全性和免疫原性。按照中国II期临床试验方案的设计和执行要求,该研究于...
Background:Trials of the Pfizer-BioNTech BNT162b2 mRNA vaccine showed 95% efficacy in preventing symptomatic disease; however, the trials excluded immunocompromised patients (ICPs). We aim at analyzing antibody response in ICPs. Methods:A prospective cohort study was conducted at Sheba Medical Center...
Toxicity grading scale for healthy adult and adolescent volunteers enrolled in preventive vaccine clinical trials, https://www.fda.gov/regulatory-information/search-fda- guidance-documents/toxicity-grading-scale-healthy-adult-and-adolescent-volunteers-enrolled-preventive- vaccine-clinical (2007). Download ...
as pregnant and lactating women were not included in the initial vaccine clinical trials. Here, we investigate the dynamics of the vaccine-specific antibody response in breastmilk and serum in a prospective cohort of ten lactating women who received two doses of the mRNA vaccine. We show that ...
Our community setting vaccine effectiveness results are consistent with immunogenicity data from clinical trials,15,16,18 which have shown that coadministration of COVID-19 and influenza vaccines does not lead to immune interference and, in some cases, may provide a stronger immune response to SIV....
Seasonal influenza vaccine efficacy and its determinants in children and non-elderly adults: a systematic review with meta-analyses of controlled trials Vaccine, 31 (2012), pp. 49-57, 10.1016/j.vaccine.2012.10.084 View PDFView articleView in ScopusGoogle Scholar 5 L. Arregoces-Castillo, J. Fe...