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Large oncosomes (LOs), specialized EVs released by cancer cells, have garnered attention for their unique role in intercellular communication. These LOs, which have shown to be actively secreted from the plasma membrane of metastatic prostate cancer cells [57], typically range from 1 to 10 ...
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(https://clinicaltrials.gov/) yielding diverse outcomes. Recently, the Food and Drug Administration granted a breakthrough device designation to the ExoDx Prostate IntelliScore test, becoming the first exosome-based liquid biopsy test to obtain such a designation. Importantly, the EPI test score ...
Logistic regression models used to test the effect of cathepsin Z on PAH were adjusted for age, sex, first two principal components and coagulation factor X.n = 463 PAH cases and 108 disease-free controls. Boxplots depict median, first and third quartiles (Q1/Q3 = IQR), and wh...
He is a human and, for the first time in two hundred years, is able to walk in the sunlight. He is, however, returned to his vampiric state by the bite of his former love, Angelique Bouchard, who has died and returned as a vampire. A character similar to Hoffman also appeared in ...
All models were able to achieve a prediction accuracy of more than 0.86 for blood culture test data (Table 1). RF was the best overall performer among them, and interpreting the RF model data with a SHAP plot (Fig. 3), the importance of the top ten feature peaks were, in order, 7,...
In studies that presented multiple stress tests, we used the average test results with the respective pooled dispersion measure. I2 and Kendall’s tau were calculated as heterogeneity measures by Hunter Smith method44,45. The prediction intervals were calculated using the “CMA prediction intervals ...