Mutations in bone morphogenetic protein receptor 2 (BMPR2) are found in approximately 80% of individuals with hereditary PAH (∼6% of PAH cases), and in up to 20% of individuals with idiopathic disease. Disease penetrance in carriers is estimated at 20%, meaning that a range of additional ...
Six cognitive phenotypes were assessed in this study: logical memory, digit symbol test score, verbal fluency, vocabulary, general cognitive ability, and general fluid cognitive ability. The logical memory phenotype (verbal declarative memory) was calculated from the Wechsler Logical Memory test, taking...