injection of either 1.8 mg/kg body weight TMAO or 100 μl 0.9% saline vehicle for assessment of Evans blue extravasation 2 h later. In both experiments, one hour before assessment animals were injected i.p. with 100 μl of a 2% (w/v) solution of Evans blue dye in 0.9% saline (...
To cause transformation of (a liquid or sol, for example) into or as if into a soft, semisolid, or solid mass. v.intr. To become coagulated:As it cooled, the sauce began to coagulate. [Middle Englishcoagulaten, from Latincoāgulāre, coāgulāt-, fromcoāgulum,coagulator; seecoagulum.]...
the data were grouped so that EC parameters were evaluated as the lowest quartile compared to all higher quartile values. In a model (adjusting for the independent and interactive effects of age, plasma tau, the ε4 allele, years since 1stmTBI), each pg/ml increase...
LPD decreased blood concentration several uremic toxins such as indoxyl sulfate and TMAO. Insulin sensitivity and beta-cell function demonstrated negative correlations with urea, TMAO, and indoxyl sulfate. Mouse studies confirmed the positive impact of LPD on glucose homeostasis but also revealed ...
found that trimetlylamine oxide (TMAO) and β-hydroxybutyric acid (β-HB) decreased in serum, whereas lipid, lactate, alanine and N-acetyl-glycoproteins increased after genipin treatment in a CUMS rat model [93]. All of these markers may be beneficial to optimize the diagnosis and even the ...
Elevated levels of TMAO in plasma are independent biomarkers of CVD for secondary prevention. The Cleveland Clinic Heart Lab commenced blood tests to measure blood TMAO levels using LC-MS/MS [118]. Although there is a broad consensus that elevated plasma TMAO levels are independent CVD biomarkers...
SCFAs: Short-chain fatty acids; TMA: Trimethylamine; TMAO: Trimethylamine N-Oxide; PGC-1α: Peroxisome proliferator-activated receptor gamma coactivator 1α; PPAR-γ: Peroxisome proliferator-activated receptor-γ; AMPK: Adenosine monophosphate-activated protein kinase; FXR: Nuclear farnesoid X receptor;...
Resveratrol Attenuates Trimethylamine-N-Oxide (TMAO)-Induced Atherosclerosis by Regulating TMAO Synthesis and Bile Acid Metabolism via Remodeling of the Gut Microbiota. MBio 2016, 7, e02210-15. [CrossRef] [PubMed] 43. Qiao, Y.; Sun, J.; Xia, S.; Tang, X.; Shi, Y.; Le, G. Effects...
A Precision Nutrition Perspective on the Effects of Eggs on Cardiovascular Risk, Taking into Account Plasma Lipid Profiles and TMAO. J. Nutr. Biochem. 2022, 100, 108906. [Google Scholar] [CrossRef] Lütjohann, D.; Meese, C.O.; Crouse, J.R., 3rd; von Bergmann, K. Evaluation of ...
Chronic oral L-carnitine supplementation drives marked plasma TMAO elevations in patients with organic acidemias despite dietary meat restrictions. JIMD Rep. 2016, 30, 39–44. 19. Abela, L.; Spiegel, R.; Crowther, L.M.; Klein, A.; Steindl, K.; Papuc, S.M.; Joset, P.; Zehavi, Y...