UrineChronic kidney diseaseRenal declineDiagnosticIntroduction: Chronic kidney disease (CKD) is a silent disease. Most CKD patients are unaware of their condition during the early stages of the disease which poses a challenge for healthcare professionals to institute treatment or start prevention. The ...
a sudden but temporary loss of kidney function, Johns Hopkins Medicine researchers found that higher levels of certain biomarkers in urine and blood can predict a patient's risk of developing chronic kidney disease (CKD).
Urine samples can provide insights on kidney conditions based not only on creatinine detection but also via other approaches such as detection of albuminuria (presence of small amounts of albumin in urine), especially in patients at increased risk for CKD such as those with hypertension, diabetes,...
If you’re at risk for kidney disease, get your kidneys checked regularly, which is done by your doctor with simple blood and urine tests. Regular testing is your best chance of identifyingChronic Kidney Disease(CKD)early if you do develop it. Early treatment is most effective and can help...
We defined renal dysfunction as eGFR<60ml/min/1.73m 2 , as measured by the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation and proteinuria as positive urine dip-stick result. Results Blood lead and cadmium levels were significantly increased in the renal dysfunction group ...
摘要: Focuses on blood pressure and urine protein levels as least risk for worsening kidney diseases. Effect of chronic kidney diseases on patients; Disorders observed in patients of chronic kidney diseases; Usefulness of antihypertensive agents in patients with chronic kidney diseases....
[33]. Most recently, Raby found that PKP4 is presented in the urine exosome in patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD) as poor treatment responder biomarker [34]. In our cohort validation, we found that PKP4 is also upregulated in IgAN compared to normal controls,...
In addition, a morning fasting midstream urine sample was collected from each participant and frozen at − 40℃. All urine samples were shipped in ambient packaging with the use of ice boxes to the clinical laboratory at the First Affiliated Hospital of Xi’an Jiaotong University in Xi’...
Chronic kidney disease (CKD) is characterized by retention of uremic solutes. Compared to patients with non-dialysis dependent CKD, those requiring haemodialysis (HD) have increased morbidity and mortality. We wished to characterise metabolic patterns in CKD compared to HD patients using metabolomics. ...
AKI severity was staged according to the Kidney Disease Improving Global Outcomes (KDIGO) criteria in each evaluation. Urine output criteria to define AKI were not used due to unreliable data collection [25].The estimated glomerular filtration rate (eGFR) was calculated using the CKD-EPI equation ...