Proteinuria is typically quantified according to the spot urine protein–creatinine ratio (UPCR) and an association with cardiovascular events has not been thoroughly investigated in chronic kidney disease (CKD) patients. We investigated whether the severity of proteinuria assessed by spot UPCR is assoc...
The purpose of this case control study was to measure urine concentration ability in ADPKD patients compared to non-ADPKD patients and healthy controls. A seventeen hour long water deprivation test was carried out in 17 ADPKD patients (CKD I-IV), 16 non-ADPKD patients (CKD I-IV), and 18 ...
In other patients, estimates based on a reformulation of the Cockroft–Gault equation are reasonably accurate. A recent study based on this relationship found a high strength of correlation between estimated and measured urine output with chronic kidney disease (CKD) studied in the African American ...
The inability to maintain normal calcium homeostasis in CKD may lead to inappropriate calcium balance. In CKD, the bone appears less able to take up calcium, at least in low-turnover states that can be present in up to 50% of patients with CKD.77 This has led to the concept of “calci...
CKD at 1 year (p = 0.006). Univariate and multivariate logistic regression revealed logeuNGAL, age, and nephrotoxic cause of AKI to be associated with CKD (Supplementary Table5). In patients with baseline CKD (n = 289), there was a 42.9% incidence of CKD progression. Univariate ...
Acute kidney injury is defined as follows: (1) an increase in serum creatinine (s-Crea) by 26.5 μmol/L (0.3 mg/dL) within 48 hours; or (2) an increase in s-Crea that is 1.5~2 times the baseline value within 7 days; or (3) urine output of < 0.5 mL kg–1 h–1 for more...
CKD: chronic kidney disease CrCL: creatinine clearance APACHE II: acute physiology and chronic health evaluation II SAPS: Simplified Acute Physiology Score SOFA: sequential organ failure assessment SIRS: systemic inflammatory response syndrome Md: median IQR: interquartile range PPV: positive...
Several studies validating spot urine PCR in patients with chronic kidney diseases (CKD) or normal kidney function have been conducted [5, 11, 12]. However, studies on the association between a spot urine PCR and 24-h urine protein (24HP) in patients with chronic glomerular nephritis (CGN)...
The red blood cells in hypophosphatemia can have a decrease in 2,3-diphosphoglycerate levels which will prevent efficient delivery of oxygen to tissues.290 The signs and symptoms of moderate to severe hypophosphatemia include decreased cardiac output, respiratory insufficiency/failure, myopathy, jitterin...
Comparison of urinary albumin and urinary total pro- tein as predictors of patient outcomes in CKD. Am J Kidney Dis. 2011;57(1):21–28. Akin D, Ozmen S. An unresolved issue: the relation- ship between spot urine protein-to-creatinine ratio and 24-hour proteinuria. J Int Med Res. ...