Tables containing these optimal foldover plans are given in the Appendix.doi:10.1016/j.jspi.2006.09.025Fei LiMike JacrouxJournal of Statal Planning & InferenceLi, F,Jacroux, M.Optimal foldover plans for blocked 2m-k fractional factorial designs. Journal of Statistical Planning and Inference . ...
On the other hand, it should be noted that ISO is commonly prescribed for conditions such as asthma and bradycardia, with the therapeutic dosages in humans being almost fivefold those that we found to be effective for disrupting tau aggregation in mice48. The present work suggests a promising...
Analysis using 35S pulse-chase labelling showed that MCL-1 decreased the turnover of Strep Tag-NOXA Bfivefold from B30 to 160 min (Figure 3b). To test whether MCL-1 was required for stabilization of NOXA, MCL-1 was depleted by RNA interference (RNAi). NOXA disappeared whereas BIM ...
The samples were diluted 100-fold with TBS, and the membranes were collected by centrifugation at 45,000 × g for 45 min at 4 °C. The membranes were then solubilized with 1% (w/v)n-dodecyl-β-d-maltoside (Calbiochem), and histidine-tagged P-gp was recovered by nickel-chelate ...
Definitive screening designOptimalityGeneralized minimum aberrationFold-overDefinitive screening designs are a new class of three-level designs which are shown superior to the classical central composite designs in response surface methodology. They can be constructed by......
Here, we consider the joint use of the foldover and the use of a different blocking scheme in the follow-up design to generate alternative combined designs that outperform the combined designs obtained using previously given procedures in terms of estimability of two-factor interactions, estimation...
Invention provides synthesis of shock-resistant polyurethane showing 4-6-fold more energy of viscous destruction as compared with epoxy-amine polymers by variation of ratio of functional groups and amount of modifying additions. EFFECT: improved method of synthesis and properties of polyurethane. 3 ...
A54145E had an MIC of 1 mg mlÀ1 in the absence of surfactant, but the MIC in the presence of 1% surfactant was increased by 32-fold. Removal of the Me group from Glu12 (A54145D) resulted in only a twofold increase in MIC (2 mg mlÀ1) in the absence of surfactant, and ...
2A). Lymphocytes from cat 7028 lysed 19 ± 2% of canine IDUA-expressing autologous fibroblasts at an E:T ratio of 20:1, which was sixfold the lysis of the nonspecific autologous targets of 3 ± 1% (P = 0.003 for specific vs. nonspecific lysis), as summarized in Table 1. There was ...
The mRNA levels in each treatment group were expressed as fold changes compared to the mean values in the control group. Data were expressed as mean ± SE (n = 6); *P < 0.05 versus control; #P < 0.05, versus the As group. 3.7. The expression of genes encoding ...