Karola JovanovicsSandor GorogJovanovics,K. et al.Bis-Indole-Alkaloid.US 4298525. 1981Bis-Indole-Alkaloid. Jovanovics,K. et al. US 4298525 . 1981US4298525 * 1979年7月27日 1981年11月3日 Richter Gedeon Vegyeszeti Gyar Rt Bis-indole-alkaloid...
药品名称 VERU-111; bisindole; sabizabulin; V-111; APP-111 药品类别 创新药; 化药; 小分子 靶点 microtubule (MT) 作用机制 microtubule抑制剂 药品简介 -- 研发机构 Veru 最高研发阶段 全球: III期临床 中国: 临床前 审评审批类型 -- 外置链接 -- VERU-111 CAS Number: -- Molecular ...
Bis-indolinone derivatives having either 2,6-disubstituted pyridine core (1a and 1b) or 1,10-disubstituted phenanthroline core (2a and 2b), already known to have antitumor activity, have been tested as potential G-quadruplex binders. Compounds 2a and 2b are able to selectively stabilize G-qua...
A new bis -indole alkaloid, spermacoceine, was isolated from the aerial parts of Borreria verticillata . Its structure was established from spectroscopic d... A.M. Baldé,L.A. Pieters,A Gergely,... - 《Phytochemistry》 被引量: 126发表: 1991年 Antiviral enantiomers of a bisindole alkaloid...
3,3-BIS-INDOLE 3,3-BIS-INDOLE(3,3-BIS-INDOLE) CAS: 化学式: 主页 产品 3,3-BIS-INDOLE 中文名3,3-BIS-INDOLE 英文名3,3-BIS-INDOLE 英文别名3,3-BIS-INDOLE
In addition to (-)-mehranine, hecubine, ibogaine, ibogaline, 19R-epi voacristine, 20-hydroxyconopharyngine and pedunculine the novel indole alkaloids 3-oxomehranine and 14α,15β-dihydroxy-N-methylaspidospermine have been isolated from the leaves and stems of Tabernaemontana bovina. The ...
A bisindole is a type of natural product formed through the oxidative dimerization of tryptophan, with potential applications as anticancer agents. AI generated definition based on: Methods in Enzymology, 2016 About this pageSet alert Discover other topics On this page Definition Chapters and Articles...
Bis-indole derived compounds such as 1,1-bis(3′-indolyl)-1-(3,5-disubstitutedphenyl) methane (DIM-3,5) and the corresponding 4-hydroxyl analogs (DIM8-3,5) are NR4A1 ligands that act as inverse NR4A1 agonists and are potent inhibitors of tumor growth. The high potency of several DIM...
bisindole alkaloid 释义 双吲哚类生物碱 行业词典 医学 双吲哚生物碱 植物学 双吲哚类生物碱
Bisindole alkaloids of the vobasine-iboga type, conodiparines A-D obtained from Tabernaemontana corymbosa exhibited cytotoxicity [IC50 (μg/mL) = 18.6–19.2] and reversed resistance [IC50 (μg/mL) = 13.5–17] in vincristine-sensitive and resistant KB cells, respectively [62]. Aspidosperma typ...