5) nuclear localization signal (NLS) 核定位信号 1. To clarify the roles of nuclear localization signal (NLS) in inhibitory effect of HSP70 on H2O2-mediated nucleolar segregation, four eukaryotic vectors pcDNA3. 为探讨核定位信号在热休克蛋白70(HSP70)抑制H2O2所致核仁损伤中的作用,采用分子克隆技术...
Liang SH, Clarke MF.A bipartite nuclear localization signal is required for p53 nuclear import regulated by a carboxyl-terminal domain. J Biol Chem 274:32699-32703 Liang S-H,Clarke MF.A bipartite nuclear localization signal is required for p53 nuclear import regulated by a carboxyl-terminal domai...
We have identified multiple potential bipartite nuclear localization signal (NLS) sequences in this region using a modified definition of the motif, and in the present study, we have expressed five of these as fusion proteins with β-galactosidase. Only one sequence (spanning amino acids 1454 to...
NuclearLocalizationSignalfromAgrobacterium VirD2withRiceImportin—a DearEditor, lntheeukaryoticcell,thenuclearenvelopeseparates genomicDNAfrOmtherestoftheceI1.butensuresamolecu— Iarcommunicationbetweenthenucleusandthecytoplasm throughthenuclearporecomplexes(NPCs),Nucleartrans— ...
Identification and characterization of a novel bipartite nuclear localization signal in the hepatitis B virus polymerase.###[Factors influencing long-term... AIM: To characterize the nuclear import of hepatitis B virus (HBV) polymerase (P) and its relevance for the viral life cycle. METHODS: Sequ...
562 Two C-terminal truncated cytoplasmic forms of topoisomerase IIα in the VP-16 selected lung cancer cell line, H209V6, have lost bipartite nuclear localization signal(s) and result from partial gene deletion and alternative splicing 来自 Elsevier 喜欢 0 阅读量: 18 作者: S.E.L. Mirski ...
The Nuclear Localization Signal of the Human Ku70 Is a Variant Bipartite Type Recognized by the Two Components of Nuclear Pore-Targeting Complex Ku protein is a complex of two subunits, Ku70 and Ku80. Ku is suspected to participate in both DNA double-strand break repair and transcription. ...