1. 1. The intracellular levels of pyrimidine nucleotides and of arginine changed markedly during the growth cycle (10 days) of Catharanthus roseus in suspension culture. 2. 2. The levels of UTP and UDP-glucose increased rapidly during the 24 hr which followed transfer of the cells to fresh ...
Analogs of pyrimidine and purine mononucleotide precursors as metabolic inhibitors 1981, Pharmacology and Therapeutics Some pyrazoles as inhibitors of purine biosynthesis de novo 1976, Biochemical Pharmacology The Regulation of Branched and Converging Pathways ...
Nucleotides also serve as energy carriers (ATP), signaling molecules (cyclic nucleotides), and cofactors (NAD+, FAD). The biosynthesis of nucleotides is a complex process that involves the synthesis of the purine or pyrimidine bases, the addition of sugar and phosphate groups, and the assembly ...
The structures of the nucleoside analogs can be classified into five groups. One group is structurally similar to the purine nucleosides or nucleotides; a second group is structurally similar to the pyrimidine nucleosides; a third group is the pyridine nucleosides; a fourth group is the diazepine ...
A majority of the mutants identified consistently by both approaches carried a deletion of a gene involved in either the purine or pyrimidine nucleotide biosynthetic pathway and showed a 20- to 1,000-fold drop in viable cell counts as compared to wild-type E. coli after 24 h of growth in ...
(c) Relative mRNA levels of genes involved in pyrimidine de novo synthesis in WT and pah1Δ cells in the log phase in minimal medium. Data are presented as mean ± SD (n = 3; n = biologically independent samples). (d,e) Volcano plots of significantly differential ...
It is proposed that ammonia stimulates the production of CP by the mitochondrial CP synthetase, which in turn would stimulatepyrimidine synthesis and result in a reduced tissue content of PRPP available for purine nucleotide biosynthesis. This work was supported in part by NIH grant #GM 07004)....
The natural occurrence and the extraordinary biological and pharmacological properties of 7-deazapurine nucleosides have been the reason for studies on the... IP Ding - 《Nucleosides Nucleotides & Nucleic Acids》 被引量: 0发表: 2009年 加载更多来源...
Biosynthesis of amino acids, nucleotides and related molecules
Chapter 18 Biosynthesis of Amino Acids , Nucleotides and Related Molecules 第18章 氨基酸,核酸,以及相关分子的生物合成 1.ATP Consumption by Root Nodules in Legumes(豆类根瘤中的ATP消耗) Bacteria residing in the root nodules of the pea plant consume more than 20% of the ATP produced by the plant...