"Liquid biopsies," one of the hottest trends in oncology, couldyield a less painful and risky...Pollack, Andrew
Individual-level data, including sex and patient age, were not collected, except for PSA levels for patients with prostate cancer. Sex and/or gender were not considered in the study design. Blood samples were collected in the tubes containing K2 EDTA (BD Biosciences, 366643), and plasma extrac...
Prostate cancer, for example, has a marker known asPSA. Higher levels of PSA in the blood (anything over 4.0 ng/mL) could be a sign of the condition. But you could have high levels of PSA and still not have the disease. For example,prostatitisor benign prostatic hypertrophy could also ...
Liquid biopsyis a broad term that refers to the analysis of tumor-derived biomarkers isolated from biological fluids of cancer patients (Fig. 1). Although peripheral blood is the main font for liquid biopsy testing, tumor biomarkers can be identified in a variety of body fluids including urine ...
impracticalforlongitudinalmonitoring,heterogeneous,orunabletoobtainsuf icienttumorcontent;thus,tissuebiopsysamplingisamajorchallengeinthetreatmentandmanagementofcancers[2].Bloodbiopsy,particularlycirculatingcell-freeDNA(cfDNA),isemergingasanon-invasivemethodforcancertargetedtherapybyidenti icationofspeci icdruggablegenetic...
Individualized tumor-informed circulating tumor DNA analysis for postoperative monitoring of non-small cell lung cancer The proposed tumor-node-metastasis-blood (TNMB) classification surpasses TNM staging for prognostic prediction at the decision point of adjuvant treatment. ... K Chen,F Yang,Haifeng ...
Breast cancer causes metabolic alteration, and volatile metabolites in the breath of patients may be used to diagnose breast cancer. The objective of this study was to develop a new breath test for breast cancer by analyzing volatile metabolites in the exhaled breath. We collected alveolar air fro...
diagnostic assay,diagnostic test- an assay conducted for diagnostic purposes blood test- a serologic analysis of a sample of blood chorionic villus biopsy,chorionic villus sampling- a prenatal test to detect birth defects at an early stage of pregnancy; tissue from the chorionic villi is assayed ...
The possibility to analyse the tumour genetic material shed in the blood is undoubtedly one of the main achievements of translational research in the latest years. In the modern clinical management of advanced non-small cell lung cancer, molecular characterisation plays an essential role. In parallel...
3. Two of his doctors said Wednesday a blood test and a biopsy of tissue from his digestive tract showed no evidence of stomach cancer. 4. All had either undergone a biopsy of the breast to check for cancer, or were scheduled for one. ...