Feasibility and safety of image-guided biopsy procedures for personalized cancer treatmentGadellaaVan Hooijdonk, C G MCirkel, G AWillems, S MKoudijs, M JDe Jonge, M J ASteeghs, NSleijfer, SSchellens, J H MVoest, E ELolkema, M P J K...
Pleural effusion containing rare disseminated metastatic tumor cells represents a valuable surrogate for the tumor tissue biopsy and allows us to interrogate the metabolic state of patient tumor cells. Pleural effusion is a common complication and often the first sign of lung cancer patients18,19. Com...
PCa: Prostate Cancer; cs-PCa: clinically-significant PCa; Sens: Sensitivity; Spec: Specificity; PPV: Positive Predictive Value; NPV: Negative Predictive Value. Discussion In our analysis of 281 biopsy procedures, we found an overall detection rate of PCa equal to 52.3% in patients who underwent...
For residual N1 nodal disease following neoadjuvant chemotherapy (NAC) for patients with breast cancer, the optimal local therapy for axilla is an evolving area. We analyzed the long-term results of these patients according to axillary surgical methods using propensity score matching (PSM) to clarify...
[1]. Given this burden, there is increasing demand for personalised cancer management and treatment selection to improve survival rates and enhance patient care. Population screening methods are available as secondary prevention strategies for some cancers but rely on invasive and expensive procedures ...
20–24 In addition, a preoperative tissue diagnosis allows patients to have a more informed and thorough discussion of cancer treatment options before surgery. Ultrasound is the guidance method of choice for percutaneous interventional procedures of nonpalpable breast lesions. In addition, ultrasound ...
proliferation. As we know, proliferating cancer cells tend to synthesize nucleotides de novo [57], and different tumor subtypes possess distinguishing nucleotide reprogramming procedures [58]. In recent decades, considerable attention has been focused on the role of nucleotide metabolism in cancer ...
In addition, on August 26, 2020, the FDA approved a liquid biopsy test fromFoundationOnethat analyzes blood samples to identify patients who might benefit from specific prostate and lung cancer drugs. FoundationOne's companion diagnostic test looks at more than 300 cancer-related genes for genomic...
For example, the shaded row is the distribution of patients not diagnosed with cancer on targeted biopsy but were ultimately found to have cancer on standard biopsy and prostatectomy. Table 1. Patient Demographics View LargeDownload All Patients Who Had BiopsyNo-Prior-Biopsy CohortProstatectomy Cohort...
However, repeating tissue biopsies to get updated information about cancer is invasive and associated with potential complications, such as pain, infection, and bleeding. Also, undergoing multiple tissue biopsy procedures can be very difficult for the patient. It requires repeat visits with attendant tr...