About Biomarkers in Medicine Biomarkers are physical, functional or biochemical indicators of physiological or disease processes. These key indicators can provide vital information in determining disease prognosis, in predicting of response to therapies, adverse events and drug interactions, and in establis...
期刊名称:《Biomarkers in medicine》 | 2016年第1期 关键词: angiogenesis; coronary artery disease; placental growth factor; soluble fms-like tyrosine kinase-1; vascular endothelial growth factor; 9.Inter-regulation of gastric emptying and incretin hormone secretion: implications for postprandial glycemi...
However, age strongly affects clinical outcome in low-risk groups of both ferritin and NLR groups; hence, it should be considered as an early predictive factor of COVID-19 disease progression.doi:10.14814/phy2.14876Haerani RasyidDepartment of Internal Medicine Faculty of Medicine Hasanuddin ...
Johnson, MD, MSCI, an assistant professor of medicine of hematology/oncology with Vanderbilt Institute, in an interview with OncLive.“We still lack a convincing biomarker that can tell us when to use an anti–PD-1 monotherapy, when to use a combination, whether either [regimen] is going to...
3. Precision medicine Precision medicine aims to tackle the heterogeneity and complexity seen in diseases as well as patient treatment response. Over the last couple of decades, the use of the term “precision medicine,” or “personalized medicine” [33] has notably increased, becoming part of ...
One of the world's leading journals in the field of translational research, Journal of Translational Medicine is dedicated to turning fundamental discoveries ...
GDF-15 is a member of the Transforming Growth Factor Beta cytokine superfamily. It is not normally expressed in the heart, but under episodes of stress (for example, ischaemia and reperfusion) its levels go up in a variety of tissues, including cardiomyocytes. It has an antihypertrophic effect...
Impact of hepatic lesions on liver and plasma proteomes Differential abundance analysis in the liver proteome (Methods) revealed 658 proteins significantly dysregulated (false discovery rate (FDR)-adjustedP < 0.05) across stages of fibrosis, 135 of inflammatory activity and 68 of steatosis, total...
Systems biology of metabolism: a driver for developing personalized and precision medicine. Cell Metab. 25, 572–579 (2017). Article CAS PubMed Google Scholar Kalhan, S. C. et al. Plasma metabolomic profile in nonalcoholic fatty liver disease. Metabolism 60, 404–413 (2011). Article CAS ...
populations of the entire proteome, the advances of this technological field will expand our knowledge of disease biology in a large scale, discover new biomarkers or biomarker panels, open a new window for more effective early diagnosis, disease surveillance, and move towards personalized medicine. ...