In this Review, the authors provide an overview of the evidence regarding the use of blood levels of glial fibrillary acidic protein as a biomarker in a range of neurological diseases, including traumatic brain injury, stroke, multiple sclerosis and Alzheimer disease. Ahmed Abdelhak , Matteo Foschi...
and validation of discovered gene or protein-based, network or dynamic network biomarkers with human diseases, patient phenotypes, or clinical applications, and accelerate the development of human disease-specific biomarkers for the early diagnosis, monitoring, evaluation, and prediction of diseases. Condi...
Serum microRNAs (miRNAs) have been reported as novel biomarkers for various diseases. But circulating biomarkers for predicting the radiosensitivity of nasopharyngeal carcinoma (NPC) have not been used in clinical practice. To screen out of differently expressed serum miRNAs from NPC patients with differ...
The National Center for Health Statistics maintains the death certificates of individuals who have passed away, and both participant deaths and the causes of death are routinely updated until December 31st, 2019. We used the International Classification of Diseases, Tenth Revision (ICD-10) to ...
The biomarkers for heterogeneous diseases often exhibit strong cooperative effects, which implies that a set of genes may achieve more accurate outcome prediction than any single gene. In this study, we evaluated various biomarker identification methods that consider gene cooperative effects implicitly or...
The present invention also provides various methods of using the biomarkers, including methods for diagnosis of inflammatory bowel disease, methods for distinguishing between inflammatory bowel diseases, methods of determining predisposition to inflammatory bowel disease, methods of monitoring progression/...
According to WHO data,[1] in 2019, the top three causes of death among men were cardiovascular diseases, malignant neoplasms, and infectious and parasitic diseases. Despite major advances in cancer research that have led to improvements in cancer treatment and declining mortality ...
Due to the overlap of various reflux symptoms with other GI pathologies, the diagnosis of GERD can be challenging. However, salivary pepsin test offers a simple and convenient way for detecting reflux through salivary sample collection, providing quick and non-invasive results. Compared to other ...
The enteric nervous system is vital for life, and its dysfunction participates not only in digestive disorders, but also in diseases of the central nervous system (CNS). Here, Rao and Gershon discuss the gastrointestinal consequences of neurological disorders, the acquisition of CNS disease in the...
Additionally, they serve as biomarkers for the diagnosis of various diseases34. In our study, hsa-mir-93-5p and hsa-mir-17-5p were found to be significantly upregulated. In a study on DEGs in peripheral blood samples of patients with SARS-CoV-2, these two miRNAs were deduced as ...