The miRNA functions as a guide by base-pairing with target mRNA to negatively regulate its expression. The level of complementarity between the guide and mRNA target determines which silencing mechanism will be employed; cleavage of target messenger RNA (mRNA) with subsequent degradation or ...
FL). Six breeding pairs ofA. ocellariswere made by pairing juvenile males together. The larger of the two males changed sex within 6 months to a year of pairing. The reproductive pairs were left alone to spawn numerous times over several years before they were sampled for this ...
Fig. 1: Scheme representing photovoltaic bioelectronics with the main topics introduced in this review. The interaction of light with biomaterials and new generation semiconductors is a dynamic field of research with numerous applications in various domains, such as biosensing, bio-photovoltaics, and bio...
a, Chromosome clustering in class of human oocytes with pre-clustered chromosomes at NEBD. Top row: Scheme illustrating chromosome configuration (chromatin in magenta; nuclear envelope in black); Rows bellow: Live human oocyte expressing H2B-mRFP1 (chromosomes) and EGFP-MAP4 (not shown). Yellow...
RNA–RNA interaction data are often encoded as multidimensional tensors to convey base-pairing information. One way to encode miRNA‒target interactions is via a 3D matrix, in which the first two dimensions represent the miRNA and target sequence positions, and the last dimension represents the ...
Fig. 11 A comprehensive scheme summarizing the changes of various genes, ncRNAs transcription and APA from NFNLs to FNLs related to sink‒source regulation. Orange and green colors represent upregulated and downregulated, respectively. Full size imageData...
methyltransferases (DRM1/2) via the small interfering RNAs (RdDM) DNA methylation pathway. Here, DICER-dependent 21- to 24-nt siRNAs direct Argonaute proteins (AGO4/AGO6) to complementary sequences in the genome, possibly through a base-pairing mechanism and siRNA:nascent RNA base pairing ...
zero value was used for that metabolite. Flux-sum values of a metabolite between the wild-type and mutant groups were considered significantly different ifPvalue from the two-sided Wilcoxon rank-sum test was less than 0.05, which, as a result, allowed pairing a metabolite with a mutated gene...
Integrins are conformationally flexible cell surface receptors that survey the extracellular environment for their cognate ligands. Interactions with ligands are thought to be linked to global structural rearrangements involving transitions between bent,
Yet another numbering scheme for immunoglobulin variable domains: an automatic modeling and analysis tool. J. Mol. Biol. 309, 657–670 (2001). Article CAS PubMed Google Scholar Dunbar, J. & Deane, C. M. ANARCI: antigen receptor numbering and receptor classification. Bioinformatics 32, 298–...