a, Chromosome clustering in class of human oocytes with pre-clustered chromosomes at NEBD. Top row: Scheme illustrating chromosome configuration (chromatin in magenta; nuclear envelope in black); Rows bellow: Live human oocyte expressing H2B-mRFP1 (chromosomes) and EGFP-MAP4 (not shown). Yellow...
Fig. 1: Scheme representing photovoltaic bioelectronics with the main topics introduced in this review. The interaction of light with biomaterials and new generation semiconductors is a dynamic field of research with numerous applications in various domains, such as biosensing, bio-photovoltaics, and bio...
The yield of major crops is generally limited by sink capacity and source strength. Cucumber is a typical raffinose family oligosaccharides (RFOs)–transporting crop. Non-coding RNAs and alternative polyadenylation (APA) play important roles in the regul
We also identified a rare class of ZIKV-cross-reactive human monoclonal antibodies with increased somatic hypermutation and broad neutralization against multiple flaviviruses. One huMAb, K8b, binds quaternary epitopes with heavy and light chains separately interacting with overlapping envelope protein dimer...
embeddings and updating these vectors via a neural network layer called the embedding layer. This method can generate word embeddings that are more relevant to the objective of the model. For example, m6Anet employs this scheme to generate motif embedding vectors79. In addition to the encoding ...
(ORF), and poly-A tail. A diagram of the protein indicates domain locations as described in Figure 3. (B) Annotated protein sequence predicted from full-length cDNA ORF (GenBank GU453173). Color scheme is the same as in Figure 3. Amino acid residues below the ZmSUN4 sequence show ...
Volume-regulated anion channels (VRACs) participate in the cellular response to osmotic swelling. These membrane proteins consist of heteromeric assemblies of LRRC8 subunits, whose compositions determine permeation properties. Although structures of the
(Extended Data Fig.1eandMethods). In the first scheme (inhibited state 1, GluA2-γ2IS-1), we mixed the CTZ-bound receptors with Glu and GYKI-52466 immediately before freezing. In the second scheme (GluA2-γ2IS-2), the receptors were preincubated with GYKI-52466 in addition to CTZ ...
(Extended Data Fig.1eandMethods). In the first scheme (inhibited state 1, GluA2-γ2IS-1), we mixed the CTZ-bound receptors with Glu and GYKI-52466 immediately before freezing. In the second scheme (GluA2-γ2IS-2), the receptors were preincubated with GYKI-52466 in addition to CTZ ...
DIANA-microT-CDS can identify miRNA targets in the 3′ untranslated region (3′ UTR) and in the CDS [149]. This algorithm uses miRNA-recognition elements (MREs) for the miRNA:mRNA base pairing. The software provides an automatic pipeline as well as plug-ins that allow the user to access...