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Initially, the catalytic activity of RNR depends on the combination of a tyrosine residue with either a di-iron-oxo species (class Ia) or a di-manganese-oxo entity (class Ib). In Escherichia coli, the RNR is composed of a 1:1 complex of two homodimeric subunits (R1 and R2) and there...
As other glia cells and neurons, oligodendrocytes are able to express major histo- compatibility (MHC) class I antigens under inflammatory conditions, which is an essential pre-requisition for antigen recognition and cytotoxicity by MHC class I restricted cytotoxic T-cells [64]. 123 44 Acta ...
Nucleartransferagus cannot interbreed with extinct mammoths, and so she would not be classifiable as a part of the species M. primigenius. 7. Internodal (ISC): Membership is determined by organisms’ position between nodes on a phylogenetic tree. While Nucleartransferagus’ genome was taken ...
For bacteria co-culture, ISC-enriched cells (ENR + CV) were differentiated in ENR and ENR + CD as previously described. After 6 days of differentiation, cell clusters were isolated as previously described. The cell pellet was resuspended in basal culture medium and plated in suspension...
All methyltransferases belong to the same EC class (EC: 2.1.1.-), but they com- prise five structural families (reviewed in ref. [12]), which appear to lack clearly discernible common ancestor (with the possible exception of Class I and SPOUT methyltrans- ferase, see above). Three ...
et al. Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system. Cell 163, 759–771, doi: 10.1016/j. cell.2015.09.038 (2015). 34. Karvelis, T. et al. Rapid characterization of CRISPR-Cas9 protospacer adjacent motif sequence elements. Genome Biol 16, 253, doi: ...
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