In contrast to other prediction tools that dynamically solve one problem at a time, the static nature of predicted reactions stored in a database is an opportunity for experimental scientists to validate the predictions in the short and long-term future. Finally, ATLASx provides an estimation on...
Chandra H, Dasgupta PR, Kamboj VP, Setty BS, Chowdhury SR, Kar AB. 1971. The nature and kinetics of biochemi- cal response of the genital organs of ovariectomized female rhesus monkeys to sex hormones. Contraception 4:253- 266.Harish Chandra , P.R. Dasgupta , V.P. Kamboj , B.S. ...
Nature Communications volume 15, Article number: 836 (2024) Cite this article 4360 Accesses 3 Citations 11 Altmetric Metrics details Abstract The Gabija system is a newly discovered bacterial immune system that consists of GajA and GajB. Here we report the cryo-EM structure of the Gabija ...
These minireviews focus on the biochemical and cellular aspects of the signaling pathways activated by RNA, both single-stranded (ss) RNA and double-stranded (ds) RNA, including the nature of the RLR and TLR sensor proteins and the adaptors through which they signal the production of IFN in ...
The chemical nature of streptolysin S′ was investigated with a purified toxin obtained by zone electrophoresis and DEAE-cellulose column chromatography (4). 关键词: CHEMISTRY, ANALYTICAL CHROMATOGRAPHY ELECTROPHORESIS EXPERIMENTAL LAB STUDY GUANINE NUCLEOTIDES NUCLEOTIDES PEPTIDES PHENOLS PHOSPHATASES PYRIMIDINE...
Discovery and development of clofarabine: A nucleoside analogue for treating cancer The treatment of acute leukaemias, which are the most common paediatric cancers, has improved considerably in recent decades, with complete response rates ... PL Bonate,L Arthaud,WR Cantrell,... - 《Nature Reviews ...
SD Bruner,DP Norman,GL Verdine - 《Nature》 被引量: 1589发表: 2000年 Cloning and characterization of a mammalian 8-oxoguanine DNAglycosylase Oxidative DNA damage is generated by reactive oxygen species. The mutagenic base, 8-oxoguanine, formed by this process, is removed from oxidatively damage...
JO Bishop,GH Beale - 《Nature》 被引量: 31发表: 1960年 Biochemical studies of the Saccharomyces cerevisiae Mph1 helicase on junction-containing DNA structures Saccharomyces cerevisiae Mph1 is a 3-5' DNA helicase, required for the maintenance of genome integrity. In order to understand the ATPase...
Enzymes made of RNA catalyze reactions that are essential for protein synthesis and RNA processing. However, such natural ribozymes are exceedingly rare, as evident by the fact that the discovery rate for new classes has dropped to one p... Z Weinberg,PB Kim,TH Chen,... - 《Nature Chemica...
Previously, it had been suggested that the GAG gene cluster had been horizontally transferred from bacteria to a common ancestor of Pezizomycotina, due to the clustered nature of the genes and the similarity to bacterial synthase-dependent exopolysaccharide biosynthetic systems5. Our findings of ...