The spatial distribution of glycosylated RNAs in single cells can be imaged using a protocol that uses an aptamer and a DNA probe that are specific for sialic acid-containing glycosylated RNAs. It can be applied to imaging other glycosylated RNAs using aptamers for other glycans. ...
Earned a chance to study chemical biology of nucleic acid at Stanford University. I show why did I decide to study abroad, how did I choose a labolatory to... Y Tahara - 《Journal of Synthetic Organic Chemistry Japan》 被引量: 0发表: 2019年 Nucleic Acids in Chemistry and Biology The ...
nucleic acid encoded reactionsnucleic acid sensingNucleic acid directed bioorthogonal reactions offer the fascinating opportunity to unveil and redirect a plethora of intracellular mechanisms. Nano‐ to picomolar amounts of specific RNA molecules serve as templates and catalyze the selective formation of ...
Many areas of nucleic acid... CJ Knill,JF Kennedy - 《International Journal of Biological Macromolecules》 被引量: 0发表: 2007年 Nucleic acids in chemistry and biology; Edited by G M Blackburn and M J Gait. pp 467. IRL Press at Oxford University Press. 1990. 22.50 in paper back. Also...
In this review, we describe some useful nucleic acid structures, particularly their interactions with the ligands and therapeutic candidates or even drugs. We summarize important information for designing novel potent drugs and for targeting nucleic acids and protein-nucleic acid complexes to treat ...
Chemical and structural biology of nucleic acids and protein-nucleic acid complexes for novel drug discovery 来自 Semantic Scholar 喜欢 0 阅读量: 102 作者:JH Gan,S Jia,Z Huang 摘要: Since nucleic acids (DNA and RNA) play very important roles in cells, they are molecular targets of many ...
Topics covered include: chemical synthesis of modified RNA expansion of the genetic alphabet in nucleic acids by creating new base pairs chemical biology of DNA replication: probing DNA polymerase selectivity mechanisms with modified nucleotides nucleic-acid-templated chemistry chemical biology of peptide ...
Nucleic-Acid Structure Database AirySanjeev, ...SandeepKaushik, inEncyclopedia of Bioinformatics and Computational Biology, 2019 Introduction Nucleic acidshave a significant role in the development of living systems. They contain wholesome interesting information related to the molecular biologists. They are...
Nucleic acid therapeutics are based on nucleic acids or closely related chemical compounds. They include antisense oligonucleotides, aptamers and small interfering RNAs, and are typically considered in cases where specific inhibition of the function of a particular gene involved in disease is thought to...
Nucleic Acids—Their Chemical Properties and Physiological Conduct, Longmans, Green and Co., London (1914) (Fragment taken from complete sentences quoted in Portugal and Cohen, 1977, p. 77) Google Scholar 34 Levene P.A., London E.S. The structure of thymonucleic acid J. Biol. Chem, 83 ...