Binding assays represent another tool to identify markers that might be used to diagnose or treat diseases. Since peptide libraries contain hundreds of peptide combinations, combining these peptides with cells or proteins can provide information on both structure-activity relationships or targets for ther...
Sartorius performs FcγR binding assays for various IgG antibody isotypes or Fc fusion proteins using SPR. We optimize the performance of FcγR binding assays in collaboration with our customers for their specific antibody therapeutic. To meet all assay needs, we offer a variety of different bind...
Assays for Penicillin – Binding Proteins (PBPs) *ELSEVIERThe Biology of Beta-Lactam Antibiotics
we present a sample-efficient, free-solution method, termed microscale thermophoresis, that is capable of analysing interactions of proteins or small molecules in biological liquids such as blood serum
Specific interactions between proteins have a fundamental role in cellular functions and are important for bio- technological applications and antibody-based assays. In the fol- lowing, we apply MST in several typical experiments to show its feasibility for use in interaction studies in the course ...
Conversely, purified viral proteins can be used to distinguish the specific composition of antibodies that may be present. Binding assays are able to identify the subclass of rabies virus antibodies, for example, IgM and IgG, by using a conjugated anti-subclass Ig antibody as the secondary ...
nucleic acids, etc. The assay is conducted to test the binding of molecules with each other. The protein binding assay focuses explicitly on protein binding and reactions with other proteins. Protein binding assays are used in antimicrobial studies, disease analysis of diseases, and R&D of drugs....
leading to the phosphorylation of particular cellular proteins and subsequent initiation of a multitude of cellular responses. Binding and hydrolysis of nucleotides plays a major role in these activities, and our nucleotide analogs and ass...
The detailed understanding of the binding of small molecules to proteins is the key for the development of novel drugs or to increase the acceptance of substrates by enzymes. Nowadays, computer-aided design of protein–ligand binding is an important tool
The invention provides methods for determining the interactions between phage-displayed proteins and test molecules. The phage-displayed proteins are contacted with a reference moie