(Hofmann, 1994). Secreted bile acids are mostly reabsorbed from the intestine and returned to the liver for recycling in a process called enterohepatic circulation. Two transporter proteins are involved in bile acid absorption in the intestine: the apical sodium-dependent bile salt transporter (ASBT...
MalabsorptionBile salt7α‐hydroxy‐4‐cholesten‐3‐oneC4SeHCATBile acid sequestrantDiarrheaSteatorrheaFecal incontinenceSummary Bile acids are manufactured in the liver, secreted into the upper small bowel to aid digestion of fats, are reabsorbed in the small bowel and recycled for re-use back to...
Bile acid malabsorption occurs when there is impaired absorption of bile acids in the terminal ileum, so interrupting the normal enterohepatic circulation. The excess bile acids in the colon cause diarrhea, and treatment with bile acid sequestrants is beneficial. The condition can be diagnosed with ...
Paumgartner G (1977) Physiology of bile secretion: bile acid-dependent bile flow. In: Bianchi L, Gerok W (eds) Liver and bile. University Park Press, Baltimore, pp 45–43 Google Scholar Kramer W, Bickel U, Buscher HG, Gerok W, Kurz G (1982) Bile salt binding polypeptides in plasm...
Bile acid malabsorption: A forgotten diagnosis? Bile acid malabsorption (BAM) is never life threatening but can cause chronic symptoms. A survey of senior British gastroenterologists was conducted to exa... U Khalid,A Lalji,R Stafferton,... - 《Clinical Medicine》 被引量: 34发表: 2010年 加...
Bile salt malabsorption in regional ileitis, ileal resection, and mannitol-induced diarrhea Fecal bile salt excretion was studied in healthy volunteers, patients with regional ileitis, and patients with ileal resection. 10 muc of carboxyl-(14)C-cholic acid was given orally. Stools and urine were ...
Identification of a region of the ileal-type sodium/bile acid cotransporter interacting with a competitive bile acid transport inhibitor. Biochemistry 41, 14916–14924 (2002) Article Google Scholar Hagenbuch, B. & Dawson, P. The sodium bile salt cotransport family SLC10. Pflugers Arch. 447, ...
Bile acid metabolism: relationship of bile acid malabsorption and diarrhea J Pediatr Gastroenterol Nutr, 2 (1983), pp. 105-121 View in ScopusGoogle Scholar 46 A. Bajor, P.G. Gillberg, H. Abrahamsson Bile acids: short and long term effects in the intestine Scand J Gastroenterol, 45 (2010...
Ileal disease or resection causes bile salt malabsorption and a reduction in the bile salt content of bile. Since cholesterol solubility requires adequate bile salt concentrations, depletion of the bile salt content of bile might, theref... RH Dowling,GD Bell,J White - Gut 被引量: 179发表: ...
The digestion and absorption of dietary long-chain triglyceride is a sequence of very complex processes. The various steps which generate the products of lipolysis, i.e. fatty acid and monoglyceride, and which facilitate their transport to the microvillu