Bile Acid Malabsorption Caused by Ileal Resection Two syndromes of bile acid malabsorption caused by ileal resection—bile acid diarrhea (cholerheic diarrhea) and fatty acid diarrhea (steatorrheic diarrhea)—have been identified, characterized, and symptomatic therapy has been developed... AF Hofmann ...
Is bile acid malabsorption underdiagnosed? An evaluation of accuracy of diagnosis by measurement of SeHCAT retention. Br Med J (Clin Res Ed). 290: 665-668.Merrick MV, Eastwood MA, Ford MJ. Is bile acid malabsorption under diagnosed? An evaluation of accuracy of diagnosis by mea- surement ...
Idiopathic bile acid malabsorption - a review of clinical presentation, diagnosis, and response to treatment. Gut 1991; 32:1004-1006.Williams AJK, Merrick MV, Eastwood MA. Idiopathic bile acid malabsorption -- a review of clinical presentation, diagnosis, and response to treatment. Gut. 1991;32...
Hofmann AF, Poley JR (1972) Role of bile acid malabsorption in pathogenesis of diarrhea and steatorrhea in patients with ileal resection. I. Response to cholestyramine or replacement of long chain triglyceride by medium chain triglyceride. Gastroenterology 62:918–925 PubMed CAS Google Scholar Tabaq...
Nineteen of 22 patients given cholestyramine treatment subsequent to the SeHCAT test had a good symptomatic response. In conclusion, the prevalence of bile acid malabsorption in this selected group with Crohn's disease is sufficiently high to justify performing the SeHCAT test in order to separate ...
Hofmann, A. F. and Poley, J. R. (1969). Cholestyramine treatment of diarrhea associated with ileal resection.New Engl. J. Med.,281, 397 ArticlePubMedCASGoogle Scholar Hofmann, A. F. and Poley, J. R. (1972). Role of bile acid malabsorption in pathogenesis of diarrhea and steatorrhea ...
Conclusion Dietary intervention is an effective treatment option for patients with symptomatic bile acid malabsorption/diarrhoea and should be routinely considered. The exact fat restriction which is effective, requires further study. Disclosure of Interest None Declared 展开 ...
Partial bile diversion may provide symptomatic relief of pruritus in these patients, cause amelioration of liver functions, and induce catch-up growth.161 The majority of PFIC type 2 patients do not respond to ursodeoxycholic acid therapy; in fact, administration of ursodeoxycholic acid to some of ...
The principal therapeutic options for symptomatic management of cholestasis are with ursodeoxycholic acid, a hydrophilic bile acid, and cholestyramine, a bile acid sequestrant.[12][11]However, new and emerging therapies, such as gene therapies, hepatocyte transplants, and stem cell infusions, are bei...
In addition, patients with bile acid malabsorption (e.g., in Crohn's disease or short bowel syndrome) may suffer from excessive fecal bile acid excretion and subsequently bile acid-induced diarrhea and steatorrhea due to the interrupted ileal negative feedback regulation of bile acid synthesis. ...