BETA-KETOACYL-COA SYNTHASE GENES, PROTEINS AND THEIR USESMALKIT AZACHIAVI SADKAADA ZAMIR
beta-Ketoacyl-acyl carrier protein (ACP) synthase III catalyzes the condensation of acetyl-CoA with malonyl-ACP in dissociated (Type II) fatty acid synthase systems. A synthase III mutant was used to localize the structural gene to the 2... JT Tsay,W Oh,TJ Larson,... - 《Journal of ...
The crystal structure of beta-ketoacyl-acyl carrier protein synthase II from Synechocystis sp. at 1.54 A resolution and its relationship to other condensin... Moche M, Dehesh K, Edwards P, Lindqvist Y, The crystal structure of beta-ketoacyl-acyl carrier protein synthase II from Synechocystis ...
Comparison of FabB, FabF, and FabH provides insights into the substrate specificities of these enzymes, and investigation of possible interactions with known β-ketoacyl-acyl carrier protein synthase inhibitors suggests FabB, FabF and FabH may be targeted simultaneously to prevent synthesis of the ...
beta-Ketoacyl-[acyl carrier protein (ACP)] synthase forms new carbon-carbon bonds in three steps: transfer of an acyl primer from ACP to the enzyme, decarboxylation of the elongating substrate and its condensation with the acyl primer substrate. Six residues of Escherichia coli beta-ketoacyl-ACP...
beta-Ketoacyl-acyl carrier protein (ACP) synthase III (the fabH gene product) condenses acetyl-CoA with malonyl-ACP to initiate fatty acid biosynthesis in ... RJ Heath,CO Rock - 《Journal of Biological Chemistry》 被引量: 0发表: 1996年 ...
A comparison of homologies of the domains of the multifunctional synthases that selectively use malonyl-CoA or methylmalonyl-CoA suggested that the acyltransferase (AT) and beta-ketoacyl synthase (KS) domains might be responsible for the substrate selectivity. To test this hypothesis, we expressed ...
Beta-Ketoacyl Synthase-Chain Length Factor beta-ketoacyl-ACP reductase Beta-ketoacyl-ACP synthase Beta-Ketoacyl-ACP Synthase I beta-ketobutyric acid beta-ketobutyric acid beta-ketobutyric acid beta-ketobutyric acid beta-ketohydrogenase Beta-ketopropane Beta-ketopropane Beta-ketopropane beta-ketoreduct...
acyl carrier protein (ACP) activity; β-ketoacyl-ACP synthase (KS) activity; acyltransferase (AT) activity; β-ketoacyl-ACP reductase (KR) activity; FabA-like β-hydroxyacyl-ACP dehydrase (DH) activity; non-FabA-like dehydrase activity; chain length factor (CLF) activity; malonyl-CoA:ACP acy...
We have developed a new radiochemical assay for β-ketoacyl-acyl carrier protein synthase, which is rapid, sensitive and does not require the presynthesis of acyl-acyl carrier protein derivatives as substrates. The assay has allowed us to study the induction of β-ketoacyl-acyl carrier protein...