Benchling's CRISPR tool eliminates tedious work by batching gRNA design and executing it up to 100x faster than leading competitor Save and export guide sequences Save your guides as oligos on Benchling, organize them using tags and folders, and clone them into CRISPR plasmids Alternatively, export...
Other ways to design CRISPR experiments on Benchling We’ve developed a whole set of tools on Benchling that you can use for your CRISPR experiments! Take a look at some of our previous blog posts to see how Benchling can best suit your CRISPR needs. Creating knockout cell lines using CRIS...
Discussion: from Single gRNA to a library of gRNA Many researchers are now familiar with using CRISPR to design a single guide RNA towards engineering a cell line or model organism of choice at a single specific locus. But that’s not the only way to harness genome engineering tools. Four ...
Designing sgRNAs that will enable efficient and specific base editing is essential when using base editing for your own research. Compared to the 0.5-20% point mutation efficiency by standard CRISPR practices [15-17], base editing typically reaches efficiencies in mammalian cell culture of 35%, a...
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