While BCG vaccine protects against severe tuberculosis (TB) in children, its effect against adult TB is questionable. Furthermore, it is not known if HIV co-infection modifies the effect of BCG. Among 352 pairs of Tanzanian TB cases and matched controls, the BCG scar was associated with a ...
Researchers in four countries will soon start a clinical trial of an unorthodox approach to the new coronavirus. They will test whether a century-old vaccine against tuberculosis (TB), a bacterial disease, can rev up the human immune system in a broad way, allowing it to better fight the vi...
As of today, there is still no vaccine that can protect against it. Specific anti-viral drugs that could treat the infection have been proposed and tested in clinical trials: the results have sometimes been promising, but not conclusive. The outcomes of the numerous randomized international ...
BACKGROUND: Results have been conflicting as to whether Bacillus Calmette-Guérin (BCG) vaccine, a non-specific stimulator of the immune function, protects, predisposes or is unrelated to the development of childhood asthma. In this systematic review and meta-analysis, we qualitatively and quantitativ...
[59]concluded that BCG protects best against bloodborne dissemination within the host rather than against primary infection. Hypotheses explaining the observed differences in vaccine efficacy include genetic plasticity in BCG strains[60], the prevalence of tuberculosis[59]or non-tuberculous mycobacterial ...
A wide range of protective efficacy has been reported for BCG vaccine in studies. However it is well known that it protects against the severe form of TB . Among the new BCG vaccines under investigation several are promising but at the phase of clinical trials.their efficacy may change ...
While BCG vaccine protects against severe tuberculosis (TB) in children its effect against adult TB is questionable. Furthermore it is not known if HIV co-infection modifies the effect of BCG. Among 352 pairs of Tanzanian TB cases and matched controls the BCG scar was associated with a reduce...
Bacillus Calmette–Guérin (BCG) vaccine has been shown to be efficacious in protecting against Mtb in early childhood and, more interestingly, at decreasing overall morbidity and mortality to other infectious diseases, suggesting that the protective mechanism of BCG is not limited to only tuberculosis...
In general, vaccination of cattle currently is not accepted in many countries because the vaccine could interfere with theskin reactionto the tuberculin test in the field (as happens in humans). Efficacy ofM. bovisBCG in protecting bovine and other animal species against tuberculous infection has ...
In the wake of the COVID-19 pandemic caused by SARS-CoV-2, questions emerged about the potential effects of Bacillus Calmette-Guérin (BCG) vaccine on the immune response to SARS-CoV-2 infection, including the neurodegenerative diseases it may contribute