随着中药成分数据库(如TCM-ID7,TCM Database,TCMID6)的出现和化合物-靶标相互作用预测方法的发展,越来越多的证据表明,结合中药成分的靶标预测和深入的网络药理学分析是分析其分子机制的可行和有力的方法。例如结合药效团建模技术和对接技术,通过构建和分析化合物-靶点-途径-疾病网络,识别丹参方成分的潜在靶点,进一步...
2023年10月31日,该论文“BATMAN-TCM 2.0: an enhanced integrative database for known and predicted linkages between traditional Chinese medicine ingredients and target proteins”在Nucleic Acids Research期刊在线发表,国家蛋白质科学中心李栋研究员、刘中扬副研究员和北京中医药大学郭淑贞教授为论文共同通讯作者,国...
中药研究常⽤的数据库和⽹站：TCMGeneDIT、BATMAN 很多同学从事的是中医药领域的科研，相对来说，中医药发表⽂章⽐较困难，能发到Scientific Reports，Oncotarget和Cellular Physiology and Biochemistry 这种5分上下的杂志上已经⽐较困 难了，虽说这⼏个杂志的声誉不太好，毕竟影响因⼦在这⾥。从基⾦的...
2.TCMID(Traditional Chinese Medicines Integrated Database):http://www.megabionet.org/tcmid/ TCMID也有类似的功能,比如我们看到关于处方二神丸的介绍: 这里看到一位中药破故纸,还以为是这个呢: 原来是这个: 破故纸,又名:补骨脂,婆固脂,胡韭子,种子入药,有补肾壮阳、补脾健胃之功能,并可治牛皮癣等皮肤病。
database backstage; 2) Integration analyses of each ingredient’s (potential) targets; 3) Comparison analyses of multiple TCMs. BATMAN-TCM also supports the input of customized ingredient list and enables the analysis of a formula/herb not in the database backstage. These analysis functions will ...
作者简介:曹铭晨(１９９３ )ꎬ男ꎬ硕士ꎬ药师ꎬ研究方向为临床药学和中药学ꎮＥ￣ｍａｉｌ:３８３６４２６６５＠ｑｑ.ｃｏｍ∗通信作者ꎬ任炜(１９７７ )ꎬ男ꎬ本科ꎬ主管药师ꎬ研究方向为临床药学ꎮＥ￣ｍａｉｌ:ｒｗ０５３２＠１２６.ｃｏｍ基于ＢＡＴＭＡＮ￣ＴＣＭ在线分析平台的浙贝母－瓜蒌配伍...
BATMAN-TCM also supports the input of customized ingredient list and enables the analysis of a formula/ herb not in the database backstage. These analysis functions will generate new knowledge absent in both current databases and literature mining, and significantly contribute to the comprehensive ...
[Objectives]To explore the molecular mechanism of Zhizi Ganjiang Decoction in the treatment of liver cirrhosis based on the network pharmacology.[Methods]The BATMAN-TCM server was used to predict the potential targets of Zhizi Ganjiang Decoction,and the GeneCards database searched for targets ...
2023年10月31日,该论文“BATMAN-TCM 2.0: an enhanced integrative database for known and predicted linkages between traditional Chinese medicine ingredients and target proteins”在Nucleic Acids Research期刊在线发表,国家蛋白质科学中心李栋研究员、刘中扬副研究员和北京中医药大学郭淑贞教授为论文共同通讯作者,...
[Methods] The BATMAN-TCM server was used to predict the potential targets of Zhizi Ganjiang Decoction, and the Gen-eCards database searched for targets related to liver cirrhosis; Cytoscape 3.5.1 software was used to construct compound-cirrhosis targ...