Heart failureMechanismsPathophysiologyReduced ejection fractionMid-range ejection fractionPreserved ejection fractionMyocardial stiffnessGeneticHeart failure (HF) syndrome is the result of the interaction of multiple mechanisms which act interdependently. The hemodynamic impairment secondary to the low cardiac ...
Does the pathophysiology of heart failure prime the incidence of cancer? Article 06 April 2017 Introduction Approximately 20–30% of patients with cancer die from cardiovascular-related causes, irrespective of the duration following their cancer diagnosis [32]. The life expectancy of patients with ca...
Diastolic heart failure: mechanisms and controversies. Novel therapeutic targets that address the pathophysiology of this disease are being actively explored, although as yet there are no proven therapies for DHF... M Ouzounian,DS Lee,PP Liu - 《Nat Clin Pract Cardiovasc Med》 被引量: 275发表:...
Endothelial dysfunction plays a crucial role in the pathophysiology of sepsis. Alterations in endothelial nitric-oxide synthase (eNOS) may contribute to th... N Matsuda,Y Hayashi,Y Takahashi,... - 《Journal of Pharmacology & Experimental Therapeutics》 被引量: 196发表: 2006年 The role of angiog...
Endothelial factors, neurohormones and cytokines in heart failure Klein, W. Dyslipidaemia and renal disease - Pathophysiology and lipid lowering therapy in patients with impaired renal function Lechleitner, M. 3-6 Czech and Slovak spirapril intervention study (CASSIS) ...
heart. During normal wound healing, myofibroblasts, which are mesenchymal cells, undergo apoptosis and disappear once upon the completion of re-epithelialization. Pathologically prolonged myofibroblast activity leads to fibrogenesis. In fact, persistent myofibroblast activation is a common feature of ...
Physiology and pathophysiology of the plasminogen system in the kidney Pflugers Arch., 469 (2017), pp. 1415-1423 CrossrefView in ScopusGoogle Scholar [59] H. Zheng, X. Liu, N.M. Sharma, Y. Li, R.U. Pliquett, K.P. Patel Urinary Proteolytic activation of renal epithelial Na+ channels...
These studies show that telomere damage is also an important mediator of the pathophysiology of cardiac aging, promotes the progression of telomere biology related to cardiomyocyte senescence, and highlights the directions for future research to treat cardiac aging. For example, the specific molecular me...
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