Bacterial toxinsParanasal sinusesInflammationEntorhinal cortexWe investigated a possible link between bacterial infestation of the oral cavity, dental health and Alzheimer's dementia (AD).Maurer, KonradRahming, SvenPrvulovic, DavidGoethe Univ Frankfurt Dept Psychiat Psychosomat Med &Psychiatry Research. ...
Pore-forming toxins (PFTs) are the most common class of bacterial protein toxins and constitute important bacterial virulence factors. The mode of action of PFT is starting to be better understood. In contrast, little is known about the cellular response to this threat. Recent studies reveal that...
Bacterial toxins represent a vast reservoir of biochemical diversity that can be repurposed for biomedical applications. Such proteins include a group of predicted interbacterial toxins of the deaminase superfamily, members of which have found application in gene-editing techniques1,2. Because previously...
- 《Toxins》 被引量: 5发表: 2015年 The role of immunization programmes bacterial toxin but also from poor environmental sanitation lack of education and limited health facilities." The prospects for transferring recent advances in... TS Jones,RJ Waldman,WH Foege - 《Health Policy Social Policy ...
Gram-positive bacterial pathogens that secrete cytotoxic pore-forming toxins, such as Staphylococcus aureus and Streptococcus pneumoniae, cause a substantial burden of disease. Inspired by the principles that govern natural toxin-host interactions, we have engineered artificial liposomes that are tailored to...
The treatment of inoperable sarcoma by bacterial toxins (the mixed toxins of the Streptococcus erysipelas and the Bacillus prodigiosus). Proc. R. Soc. Med. 3, 1–48 (1910). CAS PubMed PubMed Central Google Scholar King, I. et al. Tumor-targeted Salmonella expressing cytosine deaminase as...
or the effects of bacterial toxins. Ensuring that bacteria selectively target and kill cancer cells without affecting healthy cells is challenging. Ensuring that bacteria localize to the tumor site and do not spread to other parts of the body is essential to prevent unwanted infections and side eff...
This chapter discusses the release of biogenic amines by bacterial toxins. The changes in catecholamine contents of rabbit adrenals were assayed 3 h after the administration of 0–1 μg of endotoxin. With toxin changes of catecholamine contents were determined in brain, heart, and adrenals of ...
Bacteria-mediated DNA damage can occur either directly through the formation of toxins with genotoxic activities or indirectly as a result of the activation of cell-autonomous or immune defence mechanisms against the pathogen. Moreover, host-cell signalling routes involved in the DDR can be altered ...
Also, several bacterial pore-forming toxins can induce cellular ion dysregulation and cause NLRP3 activation, such as group B Streptococcus. Also, ion imbalance via NLRP3 mediation is found in Chlamydia pneumoniae,26,27Staphylococcus aureus,28 and Streptococcus pneumoniae.29 Cellular induction by some...