Antimicrobial resistance is becoming more widespread, and in at least one case, an organism resistant to all known antibiotics has emerged, bringing with it the potentially terrifying prospect of a modern-day p
Fortunately, a class of 2-aminoimidazole (2-AI) compounds can bind bacterial response regulators, inhibiting biofilm formation and resensitize multidrug resistant bacteria to antibiotics. This work highlights the interactions between 2-AIs and the biofilm response regulators BfmR from Acinetobacter ...
This interaction presents a potential environment for the emergence and survival of bacterial strains resistant to antibiotics. Microplastics provide a surface that supports the growth of bacteria and thus these become a suitable substratum where ARGs increase and spread, making the problem of antibiotic...
Plasmids are thought to play a key role in bacterial evolution by acting as vehicles for horizontal gene transfer, but the role of plasmids as catalysts of gene evolution remains unexplored. We challenged populations of Escherichia coli carrying the blaT
Speeding up evolution We don’t know why triclosan has these effects, but one explanation might lie in the different ways that antibiotics and antibacterials work. Most antibiotics kill bacteria by interfering with essential steps in their life cycle, such as making new cell walls when a bacteriu...
Antibiotic-resistant bacteria as pollution indicators It has emerged from many studies that antibiotic-resistant and multiple-antibiotic-resistant bacteria (MARB) have become increasingly widespread, primarily due to overuse of antibiotics in clinical therapeutics and in livestock growth promotion. The sourc...
Antibiotic Resistant Bacteria
“bacterial resistome” divided into: intrinsic resistance, which refers to a group of organisms that become resistant to certain antibiotics without being transferred with genetic material and may be acquired through mutations. On the other hand, extrinsic resistance occurs exclusively through horizontal ...
Bacteria have become resistant to antibiotics due to selection pressures. How do resistant bacteria process antibiotics when exposed to it, compared to non-resistant bacteria? How can we understand antibiotic resistance in terms of evolution? Explain how antimicrobial resistance, superbugs affects human ...
Exposure to existing antibiotics can imbue infectious bacteria with resistance that also kicks in against new drugs related to the originals. Christopher Intagliata reports.