近日,上海交通大学医学院附属第六人民医院崔德荣教授团队和上海交通大学药学院郭圣荣教授团队在Biomaterials.(IF:12.8,一区TOP期刊)杂志上发表题为“Invasive metastatic tumor-camouflaged ROS responsive nanosystem for targeting therapeutic brain...
Given the prominent role of adenosine mediated immunosuppression and resistance to ICD induction in tumor microenvironment, combination strategies that involve ICD induction and adenosine signaling blockade are further warranted. In the present study, we investigated the antitumor effect of caffe...
验证数据 Figure 1. hPDL1 expression in B16F10-hPDL1 cell lines. Figure 2. Tumor growth curve of B16F10-hPDL1 syngeneic model (n=5). Figure 3. Body weight change of B16F10-hPDL1 syngeneic model (n=5). Figure 4. The expression of hPDL1 in humanized modified tumors by FACS ...
Figure 2. Tumor growth curve of B16F10 and B16F10-OVA-Luc syngeneic model (n=5). Figure 3. The expression of OVA in tumors by Western Blot. 相关品系 Panc02-OVA-Luc 细胞系名称:Panc02-OVA-Luc 目录号:NMC-230050 MC38-OVA-Luc (2) ...
Mechanism of tumor cell resistance to lysis by syngeneic lymphocytes. Cancer Res. 37: 3945-3956, 1977. PubMed: 908034 Fidler IJ, Kripke ML. Metastasis results from preexisting variant cells within a malignant tumor. Science 197: 893-895, 1977. PubMed: 887927 Briles EB, Kornfeld S. ...
veill ance through the novel mechan i sm of releasing nit ri c oxide to induce dysfunction of immunocytes[ J] .Melanoma Res,2001,11( 6) :559 — 5 6 7 . [9 ] Gorter A,Meri S.Immune evasion of tumor cells using membrane-
KEYWORDS:TMP;tumormetastasis;angiogenesis;VEGF;MMPs IV 英文缩略词 AO bFGF CM CAM DMEM DMSO EDl’A sACA HE 讯nrEC LSGS MMP MTT ～ⅣD OD PBS TMP VEGF VEGFR 英文缩略词 acridine orange basicfibroblast growth factor conditionedmedium chorioallantoicmembrane ...
Moreover, it inhibited the in vivo B16F10 tumor growth and increased the survival rate of mice. Greater number of Annexin V-FITC and propidium iodide (PI)-positive tumor cells signified that COR-D induced apoptosis in vivo also. The reduction in tumor growth is well correlated with decreased...
Tumor sizes, growth, and survival were all assessed. Treatment responses were characterized by flow cytometric analysis of tumor infiltrate. Vaccine-specific T-cells were delineated by gp10025-33 stimulation followed by intracellular cytokine staining for IFN-γ and assessment by flow cytometry. The ...
Normalization of the tumor cell inoculum to lung mass yielded similar results. PNX had no effect on growth of sub-cutaneous B16F10 melanoma tumors, suggesting that experimental melanoma metastasis was enhanced by local alterations in the lung microenvironment. These results suggest (1) that PNX is ...