【Key words】PDL1；Stable expression；B16F10cell lines 细胞程序性死亡配体1（Programmed cell death ligand1，PD－L1）属于B7超家族成员，主要表达在B 细胞、巨噬细胞等抗原提呈细胞表面［1］。PD－L1的受体为PD－1，其胞质区含有免疫受体酪氨酸抑制基序，为抑制性的受体。静止的T细胞不表达PD－1受体，T细胞...
The pretreatment of PD098059 blocked the increase in cell migration. Furthermore, CRH induced the phosphorylation of ERK1/2. The maximum activation of ERK1/2 by CRH was observed at 15聽min. Taken together, these results suggest that CRH is an important mediator that regulates the migration of...
(PFHig•urraed1iBca).lsTihneafedroriscer-dedepuecinndgeannt tmioaxnidnaenrtapt ocownecre(nFtRraAtiPo)nassosfay 50u–s2e0s0tµhge/pmriLncainpdlesthhoawt ecdolsoirglensifis cFaen3t+–DTPPPTHZ risadreicdaul csecdavteongstirnognagclytivbiltuyefrFoem2+–5T0PµTgZ/mwLith (Faignutiro...