本研究构建了稳定表达小鼠PDL1的B16F10转染细胞，为探讨PDL1/PD1信号通路在肿瘤免疫逃逸中的作用奠定 基金项目：国家自然科学基金（81001308、81373130）；江苏省研究生科研与实践创新计划项目（KYCX19－2121）作者单位：225001江苏扬州，扬州大学医学院 通信作者：钱莉，Email：qianl@yzu．edu．cn 了物质基础。一、材料...
International Journal of Molecular Sciences Article Zerumbone, a Tropical Ginger Sesquiterpene of Zingiber officinale Roscoe, Attenuates α-MSH-Induced Melanogenesis in B16F10 Cells Taek-In Oh 1,†, Hye-Jeong Jung 1,†, Yoon-Mi Lee 2, Sujin Lee 1, Geon-Hee Kim 1, Sang-Yeon Kan 1, ...
Programmed death ligand 1 (PD-L1) expressed on tumor cell surfaces mediates tumor-induced immunoresistance by inhibiting PD1-expressing tumor-infiltrating T cells. Here, we explored whether a soluble form of PD1 (sPD1-Ig), which blocks PD-L1, could synergize with TERT-TR-regulated HSVtk to ...