The effect of gender on vitamin B12 deficiency and anemia status was significant. Conclusion The present study has provided additional evidence regarding the lack of a causal correlation between vitamin B12 deficiency and anemia. Moreover, the prevalence of vitamin B12 deficiency and anemia was higher...
Vitamin B12(B12; also known as cobalamin) is a B vitamin that has an important role in cellular metabolism, especially in DNA synthesis, methylation and mitochondrial metabolism. Clinical B12 deficiency with classic haematological and neurological manifestations is relatively uncommon. However, subclinical...
Background: To determine the role of vitamin B12 deficiency in pernicious anemia and the efficacy of oral vitamin B12 replacement therapy given regardless of the etiology, and to compare the endoscopic and pathological findings in patients diagnosed with vitamin B12 deficiency. Methods: The study incl...
et al. Renal impairment compromises the use of total homocysteine and methylmalonic acid but not total vitamin B12 and holotranscobalamin in screening for vitamin B12 deficiency in the aged. Clin. Chem. Lab. Med. 45, 197–201 (2007). Google Scholar Carmel, R. Anemia and aging: an ...
The most common cause in adults with a prevalence of 50 to 4000 cases per 100,000 persons is a loss of intrinsic factor due to autoimmune atrophic gastritis (pernicious anemia) [2,4]. Between 2.5% and 26% of the general population is affected by vitamin B12 deficiency [5,6,7], with ...
Stage IV: Clinically evident deficiency. You get macrocytic anemia or very large red blood cells. These aren't functioning properly. You usually feel tired and weak, as well as have the earlier neurological and psychological symptoms.
In order to evaluate B12 deficiency in terms of age, the adolescents in the patient group were divided into 3 groups aged 11–13, 14–15 and 16–17. There was no significant difference between the values of the patients in terms of age (Table 3). Table 3 Distribution of vitamin...
We also did not evaluate the IF values, so we cannot establish how many of the subjects with B12 deficiency could have pernicious anemia as the underlying cause. We also did not determine the history of chronic gastritis with or without H. pylori infection, either via endoscopy (with histopath...
Energy and Endurance - Vitamin B12 deficiency leads to anemia, low energy, and weakness. (1) Adequate levels of vitamin B12 are necessary to maintain normal energy levels. However, in people who have normal B12 levels, taking extra B12 has not been shown to improve athletic performance or lea...
Abstract Objectives Measurement of the serum levels of vitamin B12 (VB12) is key for evaluating VB12 deficiency-dependent anemia. Immunoassay, the major method for determining VB12, tends to give false-normal results because of the presence of anti-intrinsic factor (IF-Ab) or other factors s...