Hence, the diagnosis of vitamin B12 deficiency was confirmed retrospectively. Vitamin B12 deficiency could rarely present with neurological manifestations in the absence of anaemia. Therefore a high index of suspicion is necessary for the early diagnosis and prompt treatment in order to reverse ...
A better knowledge of the stomatological symptomtology related to this deficiency allows an early diagnosis, before the apparition of the hematological and/or neuropsychiatric manifestations. This early diagnosis presents a major interest because some neuropsychiatric manifestations are quickly irreversible. Th...
巨幼细胞性贫血 - 巨幼细胞性贫血(megaloblastic anemia)是由于DNA合成障碍产生了体积过大并且失去功能的红细胞所导致的贫血,叶酸和维生素B12均为DNA合成过程中的重要辅酶,所以巨幼细胞性贫血很多时都是因为缺乏B12所致(也可以因为缺乏叶酸),缺B12导致的巨幼细胞性贫血又称恶性贫血(pernicious anemia), 但恶性贫血更多...
It is really summed up in this statement from the research article Laboratory Diagnosis of Vitamin B12 and Folate Deficiency,“The more common neurologic symptomsare paresthesias, numbness, and ataxia, althoughdementia and psychosis may occur”That simple statement really says it all and encompasses ...
This case highlights the potential difficulty in establishing this common diagnosis due to false-negative Cbl assay results. Given its high prevalence, vitamin B12 deficiency must be included in the differential diagnosis of patients with progressive neuropsychiatric findings and/or hematologic derangements ...
Until recently, NHS hospital specialists have taken a dim view of this maverick GP’s diagnostic approach. But after a review of Dr Chandy’s work, his novel approach to the diagnosis and treatment of B12 deficiency has been cautiously approved by Dr. Jonathan Wallace, consultant haematologist ...
8. Langan RC, Zawistoski KJ. Update on vitamin B12 deficiency. Am Fam Physician. 2011;83(12): 1425-30. 9. Devalia V, Hamilton MS, Molloy AM; British Committee for Standards in Haematology. Guidelines for the...
Early diagnosis and prompt treatment of vitamin B12 deficiency before the appearance of MA symptoms are necessary to prevent irreversible neurological disorder by careful long-term follow-up of such patients. 展开 关键词: vitamin B12 megaloblastic anemia pediatrics jejunal intestine resection ...
6.BEVINS E A, PETERS J, LÉGER G C. The diagnosis and management of reversible dementia syndromes[J]. Current Treatment Options in Neurology, 2021, 23(1): 3. 7.HUDDAR A, SESHAGIRI D V, RAMAKRISHNAN S, et al. Pea...
Hematologic abnormalities with anemia may be present [2,11]. Untreated vitamin B12 deficiency can lead to coma or even death [11]. Because of the late onset of often non-specific symptoms, the diagnosis is often not established until the second half of the first year of life [11,17,18,...