We previously demonstrated that β-lapachone (β-Lap) exerts stronger anticancer activity on oxaliplatin-resistant HCT116 colorectal cancer cells (Oxp-R-HCT 116 cells) than parental HCT116 cells (p-HCT 116 cells) by downregulating the oxaliplatin resistance-related upregulated proteins (Oxp-RR-...
β-Lapachone (β-Lap) triggers apoptosis in a number of human breast and prostate cancer cell lines through a unique apoptotic pathway that is dependent up... C Tagliarino,JJ Pink,K Reinicke,... - 《Cancer Biology & Therapy》 被引量: 153发表: 2003年 Efficacy of beta-lapachone in pancre...
β-lapachone (β-lap), an NAD(P)H:quinone oxidoreductase 1 (NQO1) targeting antitumor drug candidate in phase II clinical trials, is metabolically eliminated via NQO1 mediated quinone reduction and subsequent UDP-glucuronosyltransferases (UGTs) catalyzed glucuronidation. This study intends to explore...
Objective and design The purpose of this study was to evaluate the anti-inflammatory and anti-arthritic activities of 3,4-dihydro-2,2-dimethyl-2H-naphthol[1,2-b]pyran-5,6-dione (β-lapachone; β-lap)...doi:10.1007/s00011-012-0557-0Marília Maria Sitônio...