In studies concerning the interaction of B-CLL cells and Epstein-Barr virus (EBV), we encountered one patient whose cells had several unusual properties. In addition to the B-cell markers, the CLL cells expressed the exclusive T-cell markers CD3 and CD8 and carried a translocation t(18,22)...
In a previous report we showed that D47 CD1a monoclonal antibody positively labelled B-CLL cells of some patients. Six cases were selected to further characterize CD1 antigenic expression at the leukaemic cell surface using flow cytometry with a battery of six CD1a, two CD1b and two CD1c ...
Abujarour R, Groff B, Witty AD, Wang H, Tuininga K, Kodal B, Felices M, Bonello GB, Huffman J, Dailey T, Lee TT, Walcheck B, Valamehr B, Miller JS. Dual-antigen targeted off-the-shelf NK cells show dura...
The ultrastructural investigation of mitochondria in B-CLL cells during apoptosis. Arch Oncol. 2004; 12 :139–141.Brajušković GR, Skaro-Milić AB, Marjanović SA, Cerović SJ, Knežević-Ušaj SF: The ultrastructural investigation of mitochondria in B-CLL cells during apoptosis. ...
B-CLL cells experimentally infected with EBV enter DNA synthesis, produce cytokines and stimulate T-lymphocytes - Avila-Carino, Andersson, et al. - 1996Avila-Carino J, Andersson J, Mellstedt H, Klein E (1996) B-CLL cells experimentally infected with EBV enter DNA synthesis, produce cytokines ...
One characteristic of B cells that accumulate during chronic lymphocytic leukemia (CLL) is their highly heterogeneous functional responses to B cell receptor (BCR) stimulation. Leukemic B cells with very poor responses have defective rapid tyrosine phosp
BCR signaling, whether it be in a normal or malignant B-cells, leads to the formation of the CBM complex consisting ofCARD11,BCL10, andMALT1. This complex leads to activation of NFκB through direct activation of NFκB and inhibition of negative NFκB regulators. Gain-of-functionsomatic mut...
Interferons (, , gamma-IFN) Inhibit the Apoptotic Cell Death of B-Chronic Lymphocytic Leukemia (B-CLL) Cells in VitroPanayiotidis, P.Ganeshaguru, K.Jabbar, S. A. B.Hoffbrand, A. V.JOURNAL OF INTERFERON RESEARCH
15 The expression of specific phosphodiesterases in B-CLL cells favors a more targeted strategy by using specific PDE inhibitors. Kim and Lerner16 described recently that CLL cells contain transcripts for PDE 1B1, PDE 4A and PDE 4B. They further demonstrated the cAMP-dependent induction of ...
J. C. B-CLL cells express true endogenous E receptor after culture with T-cells and mitogens. Br. J. Haematol., 52: 205- 210,1982.Worman C. P. & Cawley J. C. (1982) B-CLL cells express true endogenous E receptor after culture with T cells and mitogens. Br. J. Haemat. 52...