Improved outcome in children with advanced stage B-cell non-Hodgkin`s lymphoma (B-NHL): results of the United Kingdom Children Cancer Study Group (UKCCSG) 9002 proto- col. Br J Cancer. 2000; 82: 1396-402.Atra A, Imeson JD, Hobson R, Gerrard M, Hann IM, Eden OB, et al. Improved...
Non-Hodgkin lymphoma (NHL), the most common hematological malignancy in the world [1,2], mainly (about 86% of NHL) originates from B cells [3]. B-cell NHL (B-NHL) comprises over 40 main subtypes, such as diffuse large B-cell lymphoma (DLBCL), Burkitt lymphoma (BL), mantle cell l...
Non-Hodgkin lymphoma (NHL), the most common hematological malignancy in the world [1,2], mainly (about 86% of NHL) originates from B cells [3]. B-cell NHL (B-NHL) comprises over 40 main subtypes, such as diffuse large B-cell lymphoma (DLBCL), Burkitt lymphoma (BL), mantle cell l...
Introduction B-cell non-Hodgkin lymphomas (B-NHLs) are the most frequent hematologic malignant cancers. Molecular targeted therapy is an important aspect of B-NHL treatment alongside cytotoxic chemotherapy, radiotherapy, and immunotherapy. Areas covered Molecular targeted therapies have changed the ...
HT (B-cell lymphoma) control cell line and TNF receptor associated factor 6 (TRAF6) Knock Down HT (B-Cell Lymphoma) Cell Line were stablished from the ascitic effusion of a 70-year-old man with B cell non-Hodgkin lymphoma (B-NHL) in 1983 (diffuse large cell lymphoma). ...
Epidemiology Circulating cytokines and risk of B -cell non -Hodgkin lymphoma NEW YORK UNIVERSITY Anne Zeleniuch-Jacquotte GuYianThe most consistent risk factors for mature B-cell non-Hodgkin lymphomas (B-NHLs) are conditions associated with altered immunity (i.e., immunodeficiency and autoimmune ...
B-cell non-Hodgkin's lymphoma (B-NHL) in the head and neck most commonly affected the oropharynx and the cervical lymph node in sexagenarian patients, with more than 70% of these cases being diffuse large B-cell lymphoma (DLBCL). Accordingly, B-NHL should be considered one of the most...
B‐cell NHLchildrendeveloping countriesBackgroundAn adapted LMB 96 derived protocol for B-cell non-Hodgkin lymphoma (NHL) was implemented at the pediatric oncology unit of the Children Welfare Teaching Hospital in Baghdad (Iraq) from 2000 to present. The purpose was to evaluate the feasibility and...
Bruton’s tyrosine kinase (BTK) plays a crucial role in the B-cell receptor (BCR) signaling which is essential for B-cell proliferation, differentiation, and cell migration. Aberrant BCR activation has been identified as a major pathogenic factor in several B-cell non-Hodgkin lymphoma (B-NHL)...
High densities of Tregs infiltrating the TME are associated with poor prognosis in patients with various types of solid cancers,10,11 but the role of Tregs remains controversial in B-cell non-Hodgkin lymphoma (B-NHL). Studies in follicular lymphoma (FL) from the prerituximab era using immunohis...