成熟B细胞非霍奇金淋巴瘤(B-cell non-Hodgkin lymphoma, B-NHL)占儿童和青少年非霍奇金淋巴瘤(non-Hodgkin lymphoma, NHL)的50%~60%。以伯基特淋巴瘤(Burkitt lymphoma, BL)/白血病(Burkitt leukemia, B-AL)和弥漫大B细胞淋巴瘤(diffuse lar...
近日,由韩为东教授、梁爱斌教授、钱文斌教授共为通讯作者,解放军总医院第一医学中心、川大华西医院生物治疗国家重点实验室等 10 家机构联合发布的文章提出,CAR-T 细胞治疗 B 细胞非霍奇金淋巴瘤(B-NHL)和治疗其他血液瘤所引起细胞因子释放综合征(CRS )的机制是不同的,最重要的特征是局部细胞因子释放综合征(...
聚焦NHL——3.5年延长随访结果,力证莫妥珠单抗在NHL中的疗效及安全性 为了评估莫妥珠单抗在NHL患者中的长期疗效和安全性,近期来自美国的Lihua E. Budde等人进行的一项I/II期临床研究,对莫妥珠单抗在R/R 惰性和侵袭性B细胞NHL患者...
非霍奇金淋巴瘤〈non-Hodgkin's lymphoma,NHL)是一种起源于淋巴结和其他结外淋巴组织的血液系统恶性肿瘤。 图片来源于网络 从细胞分化的角度可以分为T细胞和B细胞两型,B细胞来源的淋巴瘤约占60%-70%。B细胞非霍奇金淋巴瘤可发生于不同年龄段,其中,中老年群体较为常见,男性患者多于女性[1]。B细胞非霍奇金淋巴瘤...
B-cell non-Hodgkin lymphoma (B-NHL) is the most common type of lymphoma and is significantly heterogeneous among various subtypes. Despite of considerable advancements in treatment strategies for B-NHL, the prognosis of relapsed/refractory patients remains poor. ...
弥漫性大B细胞淋巴瘤(Diffuse large B-cell lymphoma ,DLBCL)是一类由中等大至大B淋巴样细胞构成的肿瘤,肿瘤细胞的核相当于或超过正常巨噬细胞的胞核,或大于正常淋巴细胞胞核的2倍,呈弥漫性生长模式。DLBCL是非霍奇金淋巴瘤(Non-Hodgkin Lymphoma, NHL)中最常见的类型,在细胞起源、形态学、免疫组织化学表型、分子...
B-cell non-Hodgkin lymphoma (B-NHL) is a group of malignant neoplasms originating from the lymphoid tissues, mainly the lymph nodes and the gene expression technique was used to unravel its complexity and aid in clinical decision-making.#The aims of this study were to find the significance ...
Mature B-cell non-Hodgkin lymphoma (B-NHL) constitutes a collection of relatively rare pediatric malignancies. In order to utilize administrative data to perform large-scale epidemiologic studies within this population, a two-step process was used to assemble a 12-year cohort of B-NHL patients ...
1)B-cell non-Hodgkin lymphomaB细胞性非霍奇金淋巴瘤 1.Objective:To evaluate the imaging characteristics ofB-cell non-Hodgkin lymphomaof skull base.目的:探讨颅底B细胞性非霍奇金淋巴瘤的影像学特点。 英文短句/例句 1.Clinical report on protocol B-NHL 2001 for childhood B-non Hodgkin's lymphoma儿童...
这些免疫疗法的有效性预计与帕博利珠单抗( Keytruda;Merck& Co.)相似,并且如果采取正确的联用方案,可在NHL治疗中取得一席之地。 BCL-2抑制剂,靶向肿瘤细胞存活路径的小分子药物也进入研发后期 凋亡(Apoptosis)是细胞死亡(Cell Death)重要的形式之一,BCL-2对于肿瘤细胞的抗凋亡实在是功不可没。抗凋亡蛋白Bcl-2已成...