B cells as antigen presenting cells. Cell Immunol. 2005; 14 :67–75. doi: 10.1016/j.cellimm.2006.02.005. [ Cross Ref ]Rodríguez-Pinto D. B cells as antigen presenting cells. Cellular Immunology . 2005; 238 (2):67–75.Rodriguez-Pinto, D. 2005. B cells as antigen presenting cells. ...
Subsequent epitope spreading depended on antigen presentation and was compartmentalized by major histocompatibility complex (MHC). B cells carrying two MHC haplotypes could bridge the MHC barrier between B cells that did not share MHC. Thus, B cells directly relay autoreactivity between two separate ...
研究显示,从接种HER2多肽疫苗的患者中分离HER2抗体,可以抑制表达HER2癌细胞的HER2激酶活性及其下游信号转导。 1.2B细胞抗原递呈B细胞是一类重要的专职抗原提呈细胞(antigen-presenting cells ,APC),但在肿瘤免疫治疗中,这一点经常被忽视。与树突状细胞和巨噬细胞主要通过吞噬方式递呈抗原不同,B细胞的抗原提呈主要通过BCR...
Here we show that the failure of MIsa antigen to activate PI hydrolysis applies when resting B cells are used as antigen-presenting cells (APC). By contrast, when MIsa-bearing B cells are activated for 24h by exposure to lipopolysaccharide or, more importantly, to Mlsa-reactive T cells or ...
The B cell is the initiating antigen-presenting cell. We have examined the role of B cells in antigen presentation in lymph nodes in several ways. We found that mice depleted of B lymphocytes via chronic injec... CAJ Janeway - 《Journal of Immunology》 被引量: 221发表: 1987年 Antigen-Pr...
Importantly, B cells can present cognate tumour-derived antigens to T cells, with the functional consequences of such interactions being shaped by the B cell phenotype. Furthermore, the isotype and specificity of the antibodies produced by plasma cells can drive distinct immune responses. Here we ...
①效应性B细胞(effector B cell,Beff)可产生自身抗体,如类风湿因子(rheumatoid factor,RF)和抗瓜氨酸蛋白抗体(anti-citrulline protein antibody,ACPA)等,这些抗体形成免疫复合物,沉积在关节中,并通过补体和细胞激活促进炎症过程;②B细胞作为有效的抗原提呈细胞(antigen presenting cell,APC),通过共刺激分子的表达激活...
cellsat extrafollicular sites where the T cells are present in association with antigen-presenting dendritic cells. Activated B cells enter the follicles, proliferate, and displace resting cells. They formgerminal centersand differentiate into both plasma cells that form antibody and long-livedmemory B...
Chesnut, R, Grey, HM (1981) Studies on the capacity of B cells to serve as antigen-presenting cells. J Immunol 126: pp. 1075-1079... RW Chesnut,HM Grey - 《Journal of Immunology》 被引量: 391发表: 1981年 Presentation of antigen by B cells: functional dependence on radiation dose, ...
PURPOSE: To characterize the role of B cells in the induction of anterior chamber-associated immune deviation (ACAID). METHODS: An in vitro model of the ACAID spleen was used to recapitulate the events that occur when antigen is introduced into the anterior chamber of the eye and culminates...