【翻译】杯口状核原始细胞见于急性髓系白血病已被广泛认知,它与急性髓系白血病未成熟型(FAB的AML-M1)密切相关,通常具有高原始细胞计数、正常核型、FLT3内部串联重复突变和NPM1突变。 This report describes an unusual case of B-lymphoblastic leuka...
Introduction: B- Cell lymphoblastic leukaemia of blood cancer that influences B- Lymphocytes, which are white blood cells that create within the delicate marrow of your bones (marrow) [1]. When healthy blood cells start to alter and expand out of control, this is called leukaemia. ALL is a...
B-lymphoblastic leukaemia/lymphoma (B-ALL/LBL) with hyperdiploidy is a neoplasm of lymphoblasts committed to the B-cell lineage whose blasts contain > 50 chromosomes (usually <66), typically without translocations or other structural a...
中国研究者首次成功揭示儿童B急淋MRD本质及耐药机制 2022年2月10日，Nature子刊Nature Cell Biology正式发表了研究论文——Elucidating Minimal Residual Disease of Paediatric B-cell Acute Lymphoblastic Leukaemia by Single-cell Analysis，引发领域内的广泛关注。中国医学科学院血液病医院（中国医学科学院血液学研究所）...
2022年2月10日,Nature子刊Nature Cell Biology正式发表了研究论文——Elucidating Minimal Residual Disease of Paediatric B-cell Acute Lymphoblastic Leukaemia by Single-cell Analysis,引发领域内的广泛关注。 中国医学科学院血液病医院(中国医学科学院血液学研究所)程涛教授、竺晓凡教授和清华大学古槿副教授是本文的通讯...
Vecchio LD, Fasanaro A, Schiavone EM, Ferrara F. B-cell acute lymphoblastic leukemia (B-ALL) heterogeneity (letter). Br J Haematol 1989; 72:291.Vecchio LD,Fasanaro A,Schiavone EM,Ferrara F.B-cell acute lymphoblastic leukemia(B- ALL) heterogeneity(letter).Br J Haematol 1989;72:291....
诺禾单细胞在开年迎来了新的成果,2月10日,中国医学科学院血液学研究所竺晓凡、程涛团队与清华大学古槿团队在Nature Cell Biology上发表了题为“Elucidating minimal residual disease of paediatric B-cell acute lymphoblastic leukaemia by single-cell analysis”的学术论文。本文通过单细胞转录组及单细胞VDJ测序实现了对...
[6]Theunissen PMJ,van den Branden A,Van Der Sluijs-Gelling A,et al.Understanding the reconstitution of the B-cell compartment in bone marrow and blood after treatment for B-cell precursor acute lymphoblastic leukaemia[J].Br J Haematol,2017,178(2):267-278. [7]Mielle J,Tison A,Cornec D,...
B cell leukaemia is one of the most frequent malignancies in the paediatric population, but also affects a significant proportion of adults in developed co