B-cell acute lymphoblastic leukemia (B-ALL) and Burkitt's lymphoma are generally discussed together because the distinction between the two is somewhat arbitrary. Children with an abdominal Burkitt's tumor and >25% marrow blasts are considered to have B-ALL, whereas those with <25% blasts are...
1.2024 EHA PB2351. 2.PDQ Pediatric Treatment Editorial Board. Childhood Acute Lymphoblastic Leukemia Treatment (PDQ®): Health Professional Version. 2021 Feb 4. In: PDQ Cancer Information Summaries. 3.National Cancer Inst...
[4]Suning Chen, et al. Innovative reduced-dose chemotherapy followed by blinatumomab induction therapy for successful management of treatment naive B-cell acute lymphoblastic leukemia adults: A multicenter, real-world study. P...
前B淋巴细胞白血病（Precursor B-cell Acute Lymphoblastic Leukemia，B-ALL）是一种起源于骨髓中未成熟前体B淋巴细胞的急性白血病，属于急性淋巴细胞白血病（ALL）的主要亚型（占ALL的80-85%）。 - 细胞来源：B细胞发育早期阶段（前B细胞），停滞在原始或幼稚阶段。 - 特征：骨髓中大量原始/幼稚淋巴细胞增殖，...
Here we generated 161,986 single-cell transcriptomes to analyse the dynamic changes of B-cell acute lymphoblastic leukaemia (B-ALL) at diagnosis, residual and relapse by combining single-cell RNA sequencing and B-cell-receptor sequencing. In contrast to those at diagnosis, the leukaemic cells at...
CD19-specific chimeric antigen receptor T cell (CD19 CAR T) therapy has shown high remission rates in patients with refractory/relapsed B-cell acute lymphoblastic leukemia (r/r B-ALL). However, the long-term outcome and the factors that influence the eff
B-cell Acute Lymphoblastic Leukemia-1Cells;细胞背景资料:详见相关文献介绍;细胞传代方法:1:2传代;细胞生长特性:悬浮生长;细胞形态特性:淋巴母Cells;相关细胞有:SMMC7721Cells、NCI-HUT-460Cells、LSC-1细胞 A.704Cells;细胞背景资料:详见相关文献介绍;细胞传代方法:1:3—1:4传代,每周换液2-3次;细胞生长特性:...
为了攻克这个难题,中国人民解放军西部战区总医院血液科等单位的研究人员在《Heliyon》期刊上发表了一篇名为《Rapid development of acute monocytic leukemia (AML-M5b) with t (9;11)(p22;q23) after chemotherapy for T-cell lymphoblastic lymphoma: A case report》的论文。他们通过研究发现,T-LBL 进展为 AML...
"一旦我们确定了其中的途径,我们就能找到新的药物组合来改善治疗效果。 Single-cell systems pharmacology identifies development-driven drug response and combination therapy in B cell acute lymphoblastic leukemia.Cancer Cell, 2024; 42 (4): 552 DOI:10.1016/j.ccell.2024.03.003...
Treatment structure is similar to B-cell ALL. However, due to higher CNS penetration,dexamethasoneis the preferred steroid overprednisone. Recentclinical trialshave shown that the addition ofNelarabine, which inhibitsDNA synthesis, was particularly effective in treating T-celllymphoblastic leukemia. Theref...