Efficacy and Safety of Adding Blinatumomab to First-Line Treatment for Chinese Children with B-Cell Acute Lymphoblastic Leukemia.2024 ASH Abstract 613 2.Lu J, et al. Reduced-dose chemotherapy and blinatumomab as induction treatment for newly ...
4. 2023 EHA Oral S119. 5. Lu J, et al. Reduced-dose chemotherapy and blinatumomab as induction treatment for newly diagnosed Ph-negative B-cell precursor acute lymphoblastic leukemia: a phase 2 trial. J Hematol O...
Although substantial progress has been made in the treatment of B-cell acute lymphoblastic leukemia (B-ALL), the prognosis of patients with either refractory or relapsed B-ALL remains dismal. Novel therapeutic strategies are needed to improve the outcome of these patients. KPT-9274 is a novel ...
Immunochina obtained approval of clinical trial for IM19 CAR-T cells treatment for refractory or relapse acute B-cell lymphoblastic leukemia 2020年4月21日,北京艺妙神州医药科技有限公司宣布,公司基于嵌合抗原受体T细胞(chimeric antigen receptor T cell,CAR-T)技术的IM19基因细胞药物获得国家药品监督管理局颁发...
Here we generated 161,986 single-cell transcriptomes to analyse the dynamic changes of B-cell acute lymphoblastic leukaemia (B-ALL) at diagnosis, residual and relapse by combining single-cell RNA sequencing and B-cell-receptor sequencing. In contrast to those at diagnosis, the leukaemic cells at...
此次临床研究题为:《Sequential CA19-and CD22-CART Cell Therapies for Relapsed B-Cell Acute Lymphoblastic Leukemia after Allogeneic Hematopoietic Stem Cell Transplantation》,即《序贯用CD19-和CD22-CART治疗异基因造血干细胞移植(allo-HCT)移植后复发的急性B淋巴细胞白血病(B-ALL)》。刘双又主任与展示壁报...
英文别名: B-cell Acute Lymphoblastic Leukemia-1 中文名: B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA-1人B淋巴细胞急性白血病细胞系保种库(附带STR基因图谱) 中文别名: B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA-1人B淋巴细胞急性白血病细胞系保种库(附带STR基因图谱) CBNumber: CB015054216 分子式: 分子量: 0 MOL ...
上述工作近日以题为“Treatment of pro-B acute lymphoblastic leukemia and severe plaque psoriasis with anti-CD19 CAR T cells: a case report” 发表在《Frontiers in Immunology》杂志。中国医学科学院血液病医院(中国医学科学院血液学研究所)邱少伟教授为通讯作者,硕士研究生张澳、副主任医师张广吉和护士长杨慧...
prognostic profile in pediatric B-cell precursor acute lymphoblastic leukemia.J Clin Oncol 2018;36:1240-1249. Mangum DS, Meyer JA, Mason CC, et al. Association of combined focal 22q11.22 deletion and IKZF1 alterations with outcomes inchildhood acute lymphoblastic leukemia. JAMA Oncol 2021;7:...
We have previously shown that leukemia-specific cytotoxic T cells (CTL) can be generated from the bone marrow of most patients with B-cell precursor acute leukemias. If these antileukemia CTL are to be used for adoptive immunotherapy, they must have the capability to circulate, migrate through ...