PREVALENCE OF CLINICAL DIAGNOSIS OF TEMPOROMANDIBULAR DISORDERS BASED ON DC/TMD, AXIS I IN ADULT UKRAINIANS OF DIFFERENT GENDER AND AGEKlochan, Svitlana M.Osnach, Roman H.Palyvoda, Ihor I.Savchenko, Mykola V.Chaikovskyi, Ihor H.International Journal of Clinical Dentistry...
Strikingly, clinical correlation analyses uncovered that higher SPP1 plasma levels in PMF patients correlate with a more severe fibrosis degree and a shorter overall survival. Collectively our data unveil that MAF overexpression contributes to PMF pathogenesis by driving the deranged production of the ...
1a. The information of the DMC participants in both the discovery and the expanded cohorts are shown in Table 1, and demonstrates that most of the clinical characteristics were not significantly different between the two cohorts. Thus, the lncRNAs selected in the discovery cohort are reliably ...
In inflammatory rheumatic disorders, the immune system attacks and damages the connective tissues and invariably internal organs. During the past decade, remarkable advances having been made towards our understanding on the cellular and molecular mechanisms involved in rheumatic diseases. The discovery of ...
Cell Lines and Clinical Samples U937, HL60, THP1, KG1a, and TF1 cells (DSMZ, Germany) were cultured in RPMI or Iscove modifier Dulbecco’s medium (IMDM) (for KG1a) with 10% fetal bovine serum (FBS). TF1 were cultured with addition of 2 ng/ml GM-CSF (PeproTech). Mouse embryonic...
To assess the clinical significance of METTL3 in CRC, we examined METTL3 expression in 4 independent CRC cohorts. METTL3 mRNA expression was up-regulated in 62.2% (79/127, P = .0027) of CRC tumor tissues compared to paired adjacent normal tissues in our CRC cohort (cohort 1) by qPCR ...
Results showed that the expression levels of both NE and β-catenin were associated with poor clinical stage of serous EOC. Moreover, we found that melatonin (MLT) effectively reduced the abdominal tumor burden of ovarian cancer induced by CRS, which was partially related to the inhibition of ...
Tumoral PD-L1 expression has been shown to be a predictive marker for response to anti-PD-1 targeted therapies. However, some PD-L1-positive patients of esophageal cancer did not benefit from such therapies, while some patients lack of PD-L1 still showed clinical response [10, 12], implying...
4381 Accesses 1 Altmetric Metrics details Abstract Necroptosis has emerged as a novel and crucial player in acute and chronic liver diseases. Necroptotic cells lead to the release of DAMPs including S100A9, followed by the development of necroinflammation. We previously have documented the beneficial...
clinical symptoms and long COVID symptoms. The transcription factor XBP1 in the ER plays a role in the reactivation of EBV [44]. Given the interaction of XBP1 and sigma-1 receptor in the ER, it is likely that sigma-1 receptor agonists (i.e., fluvoxamine), which may block EBV ...