Average age-specific cumu- lative risk of breast cancer according to type and site of germline mutations in BRCA1 and BRCA2 estimated from multiple-case breast cancer families attending Australian family cancer clinics. Hum. Genet. 112:542-551....
Average age-specific cumulative risks of breast cancer and ovarian cancer were estimated using a modified segregation analysis method.Results: The estimated average cumulative risk of breast cancer to age 70 years was estimated to be 52% [95% confidence interval (95% CI), 26-69%] for BRCA1 ...
Relative risks of breast cancer declined significantly with age for BRCA1-mutation carriers (P trend .0012) but not for BRCA2-mutation carriers. Risks in carriers were higher when based on index breast cancer cases diagnosed at <35 years of age. We found some evidence for a reduction in ...
Review: In women ≥40 years of age at average risk, breast cancer screening causes some harms 来自 学术范 喜欢 0 阅读量: 23 作者:SC Krager,AV Prochazka 摘要: Background and objectives: Although cancer in adolescents and young adults (AYAs) is increasingly an area of focus, there is a ...
compute the average of 同义词:average out adj. approximating the statistical norm or average or expected value "the average income in New England is below that of the nation"; "of average height for his age" 同义词:mean(a) lacking special distinction, rank, or status; commonly encountered ...
an increased risk of breast cancer due to factors identified as the result of screening or diagnosis (eg, prior diagnosis of proliferative lesions), what are the benefits, limitations, and harms associated with different screening modalities at different intervals, and how do these vary by age?
All organizations recommend mammography to screen for breast cancer but differ in the age at which to initiate mammograms, screening interval, and the age at which to stop screening. The final decision regarding breast cancer screening should be individualized based on the patient鈥檚 needs and ...
While early menopause (HR=0.36 [0.13; 0.99], p=0.003) and an age at menarche after 12 years (HR=0.77 [0.63; 0.95], p=0.047) were protective factors. We identified 3 groups at risk: lower, average, and higher, respectively. A low threshold was characterized at 1.9% of 12-year risk...
Breast MRI is also recommended for women with personal histories of breast cancer and dense tissue, or those diagnosed by age 50. Others with histories of breast cancer and those with atypia at biopsy should consider additional surveillance with MRI, especially if other risk factors are present. ...
I had to get a special waiver to join the military because of my testicular feminization. I didn’t know what that meant. Yes, I could have researched it, but this was before the age of the internet and I think I just was too scared to try and find out. Finally, at age 28, I ...