Here, we present a case of autoimmune cerebellar ataxia in an adult patient with multiple COVID-19 infections.Design/Methods: N/A.Results: A 63-year-old male with PMH of COPD presented with gait imbalance, dizziness, and falls. His symptoms started acutely one year ago during a confirmed ...
Care must be taken to avoid non-detection of this disease with possibly reversible symptoms in patients with cerebellar ataxia of unknown origin.doi:info:doi/10.1111/cen3.12381Kenichiro SatoDepartment of Neurology National Center for Global Health and Medicine Tokyo JapanNoritoshi Arai...
Neurologic symptoms are reported in approximately 6% of adults with CD, of which cerebellar ataxia is the most frequent one. EATL is an aggressive malignancy that, if untreated, leads to death due to multifocal intestinal perforation caused by refractory malignant ulcers. The prognosis of EATL is...
shown that oestrogen treatment can be neuroprotective in animal models of Parkinson's disease, cerebellar ataxia, late onset leukodystrophy, stroke and spinal cord injury, often by reducing apoptosis via upregulation of the anti-apototic genes bcl-2 and bcl-x [158,159,175–181]. Oestrogens have...
Autoimmune cerebellar ataxia (ACA) is an important differential diagnosis in patients presenting with signs and symptoms of cerebellar disease. Alongside multiple sclerosis and acute disseminated encephalomyelitis, autoantibody-associated disorders of the CNS are the most common cause of ACA. While ACA is...
GlyR is predominantly located in the caudal aspect of the brain stem, cerebellum, and spinal cord, potentially leading to brainstem symptoms, such as eye movement disorders or cerebellar symptoms like gait ataxia and poor coordination. Anti-GlyR antibody is associated with Stiff person syndrome ...
when bulbar, brainstem, or cerebellar symptoms are prominent as seen in at least 15% of patients [132,133,134]. In our experience with a large number of SPS-SD, dysphagia can be a debilitating symptom, especially in patients with co-existing cerebellar ataxia and is often accompanied by ...
The vestibulocerebellar presentation is largely indistinguishable among these conditions and is characterized by subacute onset of cerebellar symptoms over weeks to months. The diagnosis of autoimmune vestibulocerebellar syndromes is based on a combination of clinical and serological features, with a limited...
Autoimmune encephalitis is a group of disorders characterized by symptoms of dysfunction of the limbic and extra-limbic systems that occur in association with antibodies against intracellular antigens, synapses, or proteins located on the surface of nerve cells. Anti-NMDA (N-methyl-D-aspartate) recep...
shown that oestrogen treatment can be neuroprotective in animal models of Parkinson's disease, cerebellar ataxia, late onset leukodystrophy, stroke and spinal cord injury, often by reducing apoptosis via upregulation of the anti-apototic genes bcl-2 and bcl-x [158,159,175–181]. Oestrogens ...