Psychosis and Disorganized Behavior in Adults with Autism and Intellectual Disability: Case Identification and Staff-Patient InteractionPsychotic disorder in patients with moderate, severe, and profound intellectual disability has not been attended to adequately. These patients have traditionally "fallen ...
Psychosis, depression, anxiety, and OCD were addressed. Both SGAP and a high psychiatric disorder score were required to screen a psychiatric disorder. "Diagnostic overlap" was defined as more than one psychiatric disorder concurrent with autism. Psychiatric disorders and SGAP were found to be ...
The wide range of intellectual and language skills associated with autism was highlighted in Lorna Wing’s article (1981), “Asperger's syndrome: a clinical account”. This described a group of individuals, many of whom were adults, who, despite showing the core symptoms of autism were of at...
Psychosis Personality disorders Other neurodevelopmental disorders10 These mental health diagnoses in adults with undiagnosed autism may actually be a sign of autistic burnout.11 What Is Autistic Burnout? Autistic burnout is a non-medical term for a state of exhaustion autistic people can experience. Au...
in different rearrangements23. The smallest region that has been linked to neuropsychiatric disorders is contained between the breakpoints BP1 and BP2, i.e., the 15q11.2 locus. CNVs of this region are quite frequent (~1% of the population24) and cause a small but significant increase in the...
Altered prefrontal and hippocampal function during verbal encoding and recognition in people with prodromal symptoms of psychosis. Despite robust evidence of hippocampal abnormalities in schizophrenia, it is unclear whether hippocampal dysfunction predates the onset of psychosis. We us... PK Mcguire - 《...
There has been little transdiagnostic investigation of this across social cognition domains in young adults. A total of 199 young adults diagnosed with autism spectrum disorder (ASD;=53), early psychosis (EP;=51), and social anxiety disorder (SAD;=64) were compared against neurotypical controls ...
(< 32 weeks) or low birth weight, genetic or medical history that explained ASD symptoms, uncorrected auditory or visual impairment, significant psychiatric conditions (e.g., active mood disorders or psychosis, but not common comorbidities like anxiety or ADHD), and contraindications for an MRI ...
Integrating neuropsychological research on autism and psychosis to improve clinical outcomes. Nat Reviews Psychol. 2023;2:723–39. Article Google Scholar Howlin P, Moss P. Adults with autism spectrum disorders. Can J Psychiatry. 2012;57:275–83. Article PubMed Google Scholar Green MF. Impact ...
5 weeks of drug washout, consistent with the 1-week plasma half-life of suramin in mice. Our results show that purine metabolism is a master regulator of behavior and metabolism in the MIA model, and that single-dose APT with suramin acutely reverses these abnormalities, even in adults. ...