在药物动力学中,AUC(area under the plasma concentration-time curve),也就是药时曲线下面积,通常指的是药物在体内浓度与时间之间的曲线下面积。 图片来源:维基百科 - https://zh.wikipedia.org/wiki/曲线下面积_(药物代谢动力学) 药物浓度-时间曲线:这个曲线反映了药物在一段时间内的浓度变化。AUC 的计算是基...
【答案】:药-时曲线下面积:是坐标轴与药—时曲线围成的面积,可用梯形面积法进行估算,单位是g·h·L-1。它的大小与吸收进入体循环的药量成比例,是评价药物吸收程度的一个重要指标,常被用于评价制剂的生物利用度。 已赞过 已踩过< 你对这个回答的评价是? 评论 收起 推荐律师服务: 若未解决您的问题,请您详...
Area under the concentration/time curve of a substance in pharmacokinetic investigations; describes the extent of the bioavailability of a drug.doi:10.1007/978-3-211-89836-9_85Dr. med. Dr. phil. Gerhard NahlerSpringer ViennaD. Area under the Curve (AUC, the area enclosed by the inspiratory ...
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Pharmacokinetic studies by Calvert and colleagues1 have indicated that the dose of carboplatin to produce a desired area under the concentration-time curve (AUC) could be calculated, based on the patient's glomerular filtration rate (GFR), as: ...
This can be done by monitoring the plasma concentration versus time after dosing and calculating the area under the curve (AUC). 这可以通过监测血药浓度随时间后,剂量和计算曲线下面积(AUC为)。 www.syyxw.com 8. The fetal brain to maternal brain AUC ratio for morphine was 9. 5, suggesting la...
area-under-the-curve,-AUC 例句 释义: 全部 更多例句筛选 1. This can be done by monitoring the plasma concentration versus time after dosing and calculating the area under the curve (AUC). 这可以通过监测血药浓度随时间后,剂量和计算曲线下面积(AUC为)。 www.syyxw.com隐私...
AUCAsset Under Construction AUCAverage Unit Cost AUCAffiliated Ute Citizens(Utah) AUCAzhar University in Cairo AUCAssociated Underground Contractors(now Michigan Infrastructure & Transportation Association; Okemos, MI) AUCAcyclovir Area Under the Concentration-Time Curve ...
aarea under the plasma concentration-time curve from zero extrapolated to infinity (AUC) and maximum plasma concentration (Cmax) (alone and in combination with AZD9291) 区域在血浆集中时间曲线之下从零被外推到无限 (AUC) 和最大血浆集中 (单独) (Cmax和与AZD9291的组合)[translate]...
4) area under the plasma concentration-time curve 血药浓度-时间曲线下面积 1. Limited sampling strategy for the estimation of mycophenolic acid area under the plasma concentration-time curve in adult Chinese renal recipients; 有限取样法估算中国成年肾移植受者霉酚酸血药浓度-时间曲线下面积 2. ...