For dynorphin A scavenging experiments with U87 cells, 1.5 × 105U87 or U87-ACKR3 cells were distributed per well in a white 96-well plate. After 15-min incubation at 37 °C with 400 nM LIH383 or LIH383 control peptide (200 nM CXCL12 or CXCL10), dynorphin A was added at conc...
(Fig.5a–cand Supplementary Fig.6d), but not affected in intracellular replication or egress from host cells (Supplementary Fig.6e, f). Despite numerous attempts, a complete deletion of the gene could not be obtained. The kinase activity is important for RON13 function as complementation with ...
Characteristically, after 3 h of incubation, tEPEC produces localized adherence (LA) (with compact microcolonies) in HeLa/HEp-2 cells by means of BFP, whereas most aEPEC form looser microcolonies. We have previously identified nine aEPEC strains displaying LA in extended (6 h) assays (LA6)...
By means of fluorescein-labelled antibody, the primary atypical pneumonia virus was found to multiply exclusively in the cytoplasm of the epithelial cells ... Liu,C. - 《Journal of Experimental Medicine》 被引量: 232发表: 1957年 Aureomycin in the treatment of primary atypical pneumonia FINLAND M...
Role of atypical protein kinase C in estradiol-triggered G1/S progression of MCF-7 cells Mol. Cell. Biol., 24 (2004), pp. 7643-7653 View in ScopusGoogle Scholar Cho et al., 2001 S. Cho, Y.J. Choi, J.M. Kim, S.T. Jeong, J.H. Kim, S.H. Kim, S.E. Ryu Binding and re...
(including breast tissue) that line or cover the internal organs, and in situ means "in its original place." The difference between DCIS and invasive cancer is that in DCIS, the cells have not spread through the walls of the milk ducts into the surrounding breast tissue. DCIS is considered...
Because of 2 empty cells in the dose-by-design matrix (Table 1; no ineffective or intermediate dose arms exist in active-controlled trials), it was necessary to create a combined categorical dose-design variable instead of considering main effects of dose, design, and dose-by-design ...
In order to establish a successful infection in the human host, the malaria parasite Plasmodium falciparum must establish interactions with a variety of human proteins on the surface of different cell types, as well as with proteins inside the host cells. To better understand this aspect of malari...
A significant difference was observed in the response of the parental PC12 cells compared to the overexpressors and their ability to survive in the absence of NGF. Discussion In the present study, we utilized PC12 cells stably overexpressing atypical PKC isoforms to gain insight into their ...
Different notions of graph Ricci curvature have found applications in diverse areas, such as differentiating gene co-expression networks of cancer cells and healthy cells43, identifying crashes and bubbles in financial networks44,45, and community detection in complex networks46,47. Ollivier–Ricci ...