The Mayo Clinic Simple Score (MCSS) was developed to aid screening for cardiac transthyretin cardiac amyloidosis (ATTR-CM) and triage referral for additional testing. This study sought to assess the utility of MCSS in a general population of heart failure (HF) patients. Patients seen from 1/1...
The need for more treatment options for patients living with ATTR-CM is crucial to achieving the goal of better outcomes and improved quality of life. Access to this new therapy means more hope and more opportunity to improve the lives of patients with amyloidosis,” said Muriel Finkel, ...
The need for more treatment options for patients living with ATTR-CM is crucial to achieving the goal of better outcomes and improved quality of life. Access to this new therapy means more hope and more opportunity to improve the lives of patients with amyloidosis,” said Muriel Finkel, ...
In the phase 3 randomized controlled study ATTRibute-CM (Efficacy and Safety of AG10 in Subjects With Transthyretin Amyloid Cardiomyopathy), acoramidis, a transthyretin stabilizer, demonstrated significant efficacy on the primary end point. Participants with transthyretin amyloid cardiomyopathy who completed...
In 2018, on the advice of his nephew (with whom he currently lives), Milton traveled to the Mayo Clinic in Minnesota. Physicians there did a genetic test for ATTR and diagnosed him with the condition. “It took them two days to figure it out,” he says. He also learned one of the ...
Mayo Clin Proc. 2023;98(1):7–10. Rozenbaum MH, Large S, Bhambri R, et al. Impact of delayed diagnosis and misdiagnosis for patients with transthyretin amyloid cardiomyopathy (ATTR-CM): a targeted literature review. Cardiol Ther. 2021;10(1):141–59. Article PubMed PubMed Central Google ...
ProgressionVariantHereditaryWild-typeAims Transthyretin amyloid cardiomyopathy (ATTR‐CM) is a progressive, fatal disorder that remains underdiagnosed. The Tafamidis in Transthyretin Cardiomyopathy Clinical Trial (ATTR‐ACT) was the first large clinical trial to include both wild‐type (ATTRwt) and ...