Unlike muscle hypertrophy, muscle atrophy always involves a proteostatic shift in favor of catabolic versus anabolic processes1,2. Chief among these implicated catabolic changes is the activation of the autophagy-lysosome and ubiquitin–proteasome pathways, in particular the induction of muscle-specific ...
Type Ⅳ is a kind of adult spinal muscular atrophy (ASMA), which has low incidence rate and is often misdiagnosed as amyotrophic lateral sclerosis, muscular dystrophy, cervical syndrome, or others. OBJECTIVE: To observe the clinical features of 46 ASMA patients and analyze the relationship ...
Male satellite cells appear to have more mRNA related to differentiation and hypertrophy such as myogenin and MyoD compared to females [59] and appear to also have greater proliferative capacity compared to females [60, 61]. For example, it was recently found that young male mice tend to have...
Cardiorespiratory responses to exercise in patients with spinal muscular atrophy and limb-girdle dystrophy. Braz J Med Biol Res. 1987;20:565–8. 30. Carboni P, Porro G. [Usefulness of ECG in the early diagnosis of infantile spinal muscular dystrophy]. Minerva Pediatr. 1988;40:321–5. 31. ...
Type Ⅳ is a kind of adult spinal muscular atrophy (ASMA), which has low incidence rate and is often misdiagnosed as amyotrophic lateral sclerosis, muscular dystrophy, cervical syndrome, or others. OBJECTIVE: To observe the clinical features of 46 ASMA patients and analyze the relationship ...
Inhibition of Chronos leads to muscle hypertrophy through the regulation of Bmp7 [204]. In dexamethasone-induced skeletal muscle atrophy, the expression of Atrolnc-1, Dum, MAR1, lnc-MD1, and SYISL increases, while Myolinc decreases [206,207]. Knocking out SYISL alleviates dexamethasone-induced...
Myostatin and the skeletal muscle atrophy and hypertrophy signaling pathways. Cell. Mol. Life Sci. 2014, 71, 4361–4371. [Google Scholar] [CrossRef] Schakman, O.; Kalista, S.; Barbé, C.; Loumaye, A.; Thissen, J.P. Glucocorticoid-induced skeletal muscle atrophy. Int. J. Biochem. ...
Inhibition of Chronos leads to muscle hypertrophy through the regulation of Bmp7 [204]. In dexamethasone-induced skeletal muscle atrophy, the expression of Atrolnc-1, Dum, MAR1, lnc-MD1, and SYISL increases, while Myolinc decreases [206,207]. Knocking out SYISL alleviates dexamethasone-induced...
[3]. One of the prevailing ways to promote muscle hypertrophy and alleviate muscle atrophy is aerobic exercise, which enhances the protein metabolism balance within skeletal muscles [4], as well as reduces the levels of key inflammatory markers, such as Interleukin-6 (IL-6), C-reactive ...
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