The exchange between ATP generated by oxidative phosphorylation in mitochondria and extramitochondrial ADP is catalysed by a specific carrier protein located in the inner mitochondrial membrane. Although ADP/ATP transport is well characterized on physiological and kinetic grounds, its detailed mechanism at ...
Mitochondria serve a crucial role in cell growth and proliferation by supporting both ATP synthesis and the production of macromolecular precursors. Whereas oxidative phosphorylation (OXPHOS) depends mainly on the oxidation of intermediates from the tricarboxylic acid cycle, the mitochondrial production of ...
The ADP and ATP transport in mitochondria and its carrier. Biochim. Biophys. Acta 1778, 1978–2021 (2008). Article CAS PubMed Google Scholar Kunji, E. R. et al. The transport mechanism of the mitochondrial ADP/ATP carrier. Biochim. Biophys. Acta 1863, 3169 (2016). Article CAS PubMed...
2. The glycerol 3-phosphate shuttle is used to rapidly regenerate NAD+ in brain and skeletal muscle cells of mammals.3.The use of FAD enables electrons from cytosolic NADH to be transported into mitochondria against an NADH concentration gradient. The price of this transport is one molecule of ...
On the basis of comparative inhibition studies of ADP/ATP transport in intact mitochondria and inside-out submitochondrial particles, it was concluded that the atractylosides attack the mitochondrial carrier from the outside of the inner mitochondrial membrane, and bongkrekic acid from the inside. ...
XE: Xylem element; SE: Sieve element; TC: Transfer cell; PL: Plastid; ER: Endoplasmic reticulum; M: Mitochondria; N: Nucleus. Bar=1 μm 82 植物学报 49(1) 2014 图4 蚕豆幼嫩叶和库源转换叶小叶脉酸性磷酸酶的细胞化学定位 (A) 幼嫩叶片小叶脉筛分子,传递细胞和韧皮薄壁细胞中酸性磷酸酶的细胞...
Binds heme and porphyrins and functions in their ATP-dependent uptake into the mitochondria. Plays a crucial role in heme synthesis Subunit: Homodimer. Subcellular Location: Cell membrane. Mitochondrion outer membrane; Multi-pass membrane protein. Endoplasmic reticulum. Golgi apparatus. ...
The ADP and ATP transport in mitochondria and its carrier. Biochim. Biophys. Acta 1778, 1978–2021 (2008). 2. Kunji, E. R. et al. The transport mechanism of the mitochondrial ADP/ATP carrier. Biochim. Biophys. Acta 1863, 2379–2393 (2016). 3. Fiore, C. et al. The mitochondrial ...
Control of respiration and ATP synthesis in mammalian mitochondria and cells. Biochem. J. 284, 1–13 (1992). Article CAS Google Scholar Pavlova, N. N. & Thompson, C. B. The emerging hallmarks of cancer metabolism. Cell Metab. 23, 27–47 (2016). Article CAS Google Scholar Bauduin,...
The ABC proteins bind ATP and use the energy to drive the transport of various molecules across the plasma membrane as well as intracellular membranes of the endoplasmic reticulum (ER), peroxisome, and mitochondria (1, 2–3). ABC transporters contain a pair of ATP-binding domains, also known...